Genomics Inform.  2004 Jun;2(2):107-109.

HapAnalyzer: Minimum Haplotype Analysis System for Association Studies

Affiliations
  • 1Division of Epidemiology and Bioinformatics, National Genome Research Institute, National Institute of Health, 5 Nokbun-dong, Eunpyeng-gu, Seoul, 122-701, Korea. insong@nih.go.kr

Abstract

SUMMARY: HapAnalyzer is an analysis system that provides minimum analysis methods for the SNP-based association studies. It consists of Hardy-Weinberg equilibrium (HWE) test, linkage disequilibrium (LD) computation, haplotype reconstruction, and SNP (or haplotype)-phenotype association assessment. It is well suited to a case-control association study for the unrelated population.

Keyword

SNP; haplotype; haplotype block; disease association
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