Cancer Res Treat.  2006 Feb;38(1):1-6.

Tissue Array Methods for High-throughput Clinicopathologic Research

Affiliations
  • 1Department of Pathology, Seoul National University Bundang Hospital, Seongnam, Korea.
  • 2Department of Pathology, Seoul National University College of Medicine, Seoul, Korea. woohokim@snu.ac.kr

Abstract

Recent research in molecular biology has identified a significant number of novel markers, which may have diagnostic, prognostic and therapeutic significance. High-throughput tissue array method facilitates the validation of novel markers by enabling the simultaneous analysis of hundreds or thousands of tissue specimens. Tissue array slides can be analyzed using techniques such as immunohistochemistry and in situ hybridization. In this review, we give a brief overview of tissue array method and its application to high throughput clinicopathologic research.

Keyword

Tissue array; Translational research; Immunohistochemistry; In situ hybridization

MeSH Terms

Immunohistochemistry
In Situ Hybridization
Molecular Biology
Translational Medical Research
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