J Rhinol.  2016 May;23(1):24-30. 10.18787/jr.2016.23.1.24.

Correlation Between Salivary Alpha-Amylase Level and Heart Rate Variability in Pediatric Subjects with Sleep-Disordered Breathing

• Hwang SH
• Lee HK
• Kim RH
• Lee SH
• Ko G
• Park CS

• KMID: 2165151
• DOI: http://doi.org/10.18787/jr.2016.23.1.24

Abstract

BACKGROUND AND OBJECTIVES
The aim of this study was to evaluate the relationship between salivary alpha-amylase (sAA) and heart rate variability (HRV) indices in SDB children based on objective parameters of polysomnography (PSG). MATERIALS AND METHOD: This prospective study enrolled 67 children who underwent a physical examination and full-attended in-lab PSG with continuous electrocardiographic signal. The sAA were measured at night before PSG and in the early morning after PSG.
RESULTS
The subjects were divided into control [n=26, apnea-hypopnea index (AHI)≤1] and obstructive sleep apnea syndrome (OSAS, n=41, AHI>1) groups; the OSAS group was subdivided into mild (1CONCLUSION
TAlthough both HRV and sAA were useful methods of predicting severe OSAS in children, a weak correlation between HRV and sAA was shown in pediatric OSAS subjects. Therefore, HRV and sAA may be independent parameters revealing different aspects of pediatric OSAS.

Keyword

Child; Heart rate; Saliva; Alpha-Amylases; Sleep apnea syndromes; Correlation; Polysomnography

MeSH Terms

alpha-Amylases*
Child
Electrocardiography
Heart Rate*
Heart*
Humans
Methods
Physical Examination
Polysomnography
Prospective Studies
Saliva
Sleep Apnea Syndromes*
Sleep Apnea, Obstructive
alpha-Amylases

Reference

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