Ann Dermatol.  2000 Dec;12(4):295-298. 10.5021/ad.2000.12.4.295.

Myxoid Myofibromatosis-type Perivascular Myoma Showing Prominent Verocay Body-like Formation

• Jang KA
• Ahn SJ
• Choi JH
• Lim YS
• Sung KJ
• Moon KC
• Koh JK

• KMID: 2164004
• DOI: http://doi.org/10.5021/ad.2000.12.4.295

Abstract

Differential diagnoses showing Verocay body-like formation include schwannoma, palisading myofibroblastoma, palisading cutaneous fibrous histiocytoma, dermatofibroma with myofibroblastic differentiation, leiomyoma, palisaded encapsulated neuroma, and neuroma. A 60-year-old Korean man presented with a 10-year-history of an asymptomatic nodule on the right forearm. Histopathological examination revealed well-circumscribed multi-micronodules with prominent Verocay body-like formation consisted of spindle cells and extensive infiltrate of mutinous materials. The spindle cells were negative for S-100 protein and desmin, but positive for vimentin and a-smooth muscle actin by immunohistochemical staining. The micronodules were lined by CD34 and factor VIII positive endothelial cells. The mutinous materials were stained with alcian blue at pH 2.5, but not at pH 0.5. We diagnose it as myxoid myofibromatosis-type perivascular myoma showing Verocay body-like formation.

Keyword

Verocay body-like; Perivascular myoma

MeSH Terms

Actins
Alcian Blue
Desmin
Diagnosis, Differential
Endothelial Cells
Factor VIII
Forearm
Histiocytoma, Benign Fibrous
Humans
Hydrogen-Ion Concentration
Leiomyoma
Middle Aged
Myofibroblasts
Myoma*
Neoplasms, Muscle Tissue
Neurilemmoma
Neuroma
S100 Proteins
Vimentin
Actins
Alcian Blue
Desmin
Factor VIII
S100 Proteins
Vimentin