Tuberc Respir Dis.  2000 Sep;49(3):365-371. 10.4046/trd.2000.49.3.365.

A case of primary diffuse nodular pulmonary amyloidosis localized in the lung

• Jung SK
• Oh J
• Roh YW
• Kong HS
• Park KY
• Park JW
• Park JK
• Nam GH
• Ha SH
• Lee HK
• Jeong SH

• KMID: 2160286
• DOI: http://doi.org/10.4046/trd.2000.49.3.365

Abstract

Nodular pulmonary amyloidosis is one of the rare manifestation of amyloid disease. It is known to be caused by anyloid L fibrils in the majority of case. We experienced an unusual case of a forty-one year-old woman who was presented with multiple nodular lesion on the chest X-ray. CT-guided core needle bilpsy, performed on the lesion, showed apple green birefringes, when stained Congo red and examined under polarized light. Ultrastructurally, there are randomly oriented, forming densed networks, and consists of fine, 7.5 to 10nm diameter, rigid, non-branching filaments of various lengths in electron-microscopic finding. We report a case of primary diffuse nodular pulmonary amyloidosis only localized in the lung, which was confirmed by CT guided core needle biopsy.

Keyword

Amyloidosis; Lung; Core neddle biopsy

MeSH Terms

Amyloid
Amyloidosis*
Biopsy, Large-Core Needle
Congo Red
Female
Humans
Lung*
Needles
Thorax
Amyloid
Congo Red