Korean J Psychosom Med.  2015 Dec;23(2):114-120. 10.0000/kjpm.2015.23.2.114.

Risk Factors for Depression of Patients with Tuberculosis in Tuberculosis Specialty Hospital

• Wang JH
• Park CS
• Kim BJ
• Lee CS
• Cha B
• Lee SJ
• Lee D
• Seo JY
• Ahn I
• Chul BJ
• Kang HS
• Moon SH

• KMID: 2158472
• DOI: http://doi.org/10.0000/kjpm.2015.23.2.114

Abstract

OBJECTIVES
This study aimed to investigate the risk factors of depression for patients with tuberculosis(TB).
METHODS
A total of 57 patients with TB were recruited. All participants completed the Becks Depression Inventory-II for evaluating depressive symptoms. The risk factor for depression was analyzed by binary logistic regression analysis. Nomogram was performed for probability of depression.
RESULTS
Low body mass index(BMI, OR 0.801, 95% CI 0.65, 0.98), interruption of treatment for TB(OR 5.908, 95% CI 1.19, 29.41), past history of depression(OR 24.653, 95% CI 1.99, 308.44) were associated with increased risk for depression. The calibration curve for predicting probability of survival showed a good agreement between the nomogram and actual observation(Original C-index=0.789, bias corrected C-index=0.754).
CONCLUSIONS
The result of the present study indicate that low BMI, interruption of treatment for TB, and past history of depression were risk factors for depression in patients with TB. The psychiatric intervention may be needed to prevent depression if the patients with TB have risk factor during treatment for TB.

Keyword

Tuberculosis; Depression; Risk factors

MeSH Terms

Bias (Epidemiology)
Calibration
Depression*
Humans
Logistic Models
Nomograms
Risk Factors*
Tuberculosis*