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Prediction Model for Massive Transfusion in Placenta Previa during Cesarean Section

Kang J, Kim HS, Lee EB, Uh Y, Han KH, Park EY, Lee HA, Kang DR, Chung IB, Choi SJ

PURPOSE: Recently, obstetric massive transfusion protocols have shifted toward early intervention. This study aimed to develop a prediction model for transfusion of ≥5 units of packed red blood cells (PRBCs)...
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External Validation of the ELAPSS Score for Prediction of Unruptured Intracranial Aneurysm Growth Risk

van Kammen MS, Greving JP, Kuroda S, Kashiwazaki D, Morita A, Shiokawa Y, Kimura T, Cognard C, Januel AC, Lindgren A, Koivisto T, Jääskeläinen JE, Ronkainen , Pyysalo L, Öhman J, Rahi M, Kuhmonen J, Rinne J, Leemans EL, Majoie CB, Vandertop , Verbaan D, Roos YB, van den Berg R, Boogaarts , Moudrous W, van den Wijngaard IR, Hove LT, Teo M, St George , Hackenberg KAM, Abdulazim , Etminan N, Rinkel GJ, Vergouwen

BACKGROUND AND PURPOSE: Prediction of intracranial aneurysm growth risk can assist physicians in planning of follow-up imaging of conservatively managed unruptured intracranial aneurysms. We therefore aimed to externally validate the...
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Quantification of the Bioactive Components of the Rhizomes of Curcuma wenyujin and Assessment of Its Anti-inflammatory Effect in Benign Prostatic Hyperplasia-1 Cells

Seo CS, Park E, Lee MY, Shin HK

In this study, the marker compounds of Curcumae Rhizoma (CR) were simultaneously quantified by high-performance liquid chromatography equipped with a photodiode array detector and the anti-inflammatory effects of CR extract...
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External Validation of 3 Risk Scores in Adults with Congenital Heart Disease

Ramchandani BK, Polo L, Sánchez R, Rey J, González , Díez J, Aroca A

BACKGROUND AND OBJECTIVES: Adults with congenital heart disease (CHD) are an increasing group of patients thanks to the survival of over 85% of children with CHD. 20% of these patients...
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Evaluation of Matrix Effects in Quantifying Microbial Secondary Metabolites in Indoor Dust Using Ultraperformance Liquid ChromatographeTandem Mass Spectrometer

Jaderson M, Park JH

BACKGROUND: Liquid chromatographyetandem mass spectrometry (LC-MSMS) for simultaneous analysis of multiple microbial secondary metabolites (MSMs) is potentially subject to interference by matrix components. METHODS: We examined potential matrix effects (MEs) in...
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Simultaneous Analysis of Four Standards of The Herbal Formula, DF-02, of Ephedra intermedia and Rheum palmatum, using by High Performance Liquid Chromatography-Ultraviolet Detector (HPLC-UVD)

Choi SY, Jeong B, Jang HS, Lee J, Kwon YS, Yoon Y, Shin SS, Yang H

The herbal formula, DF-02, consisting of Ephedra intermedia and Rheum palmatum are used for the treatment of the metabolic diseases such as obesity and liver fibrosis in Korean local clinics....
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Histological Method to Study the Effect of Shear Stress on Cell Proliferation and Tissue Morphology in a Bioreactor

Chabanon M, Duval H, Grenier J, Beauchesne C, Goyeau B, David B

BACKGROUND: Tissue engineering represents a promising approach for the production of bone substitutes. The use of perfusion bioreactors for the culture of bone-forming cells on a three-dimensional porous scaffold resolves...
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Nomogram for accurate prediction of breast and axillary pathologic response after neoadjuvant chemotherapy in node positive patients with breast cancer

Choi HJ, Ryu JM, Kim I, Nam SJ, Kim SW, Yu J, Lee JE, Lee SK

PURPOSE: Many patients with cytology proven node-positive breast cancer receive a neoadjuvant chemotherapy (NAC) treatment. We developed a nomogram to predict the breast and axillary pathologic complete responses (pCR) in...
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Quantification of apixaban in human plasma using ultra performance liquid chromatography coupled with tandem mass spectrometry

Jeong HC, Kim TE, Shin KH

Apixaban, an inhibitor of direct factor Xa, is used for the treatment of venous thromboembolic events or prevention of stroke. Unlike many other anticoagulant agents, it does not need periodic...
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Development of a Label-Free LC-MS/MS-Based Glucosylceramide Synthase Assay and Its Application to Inhibitors Screening for Ceramide-Related Diseases

Fu Z, Yun SY, Won JH, Back MJ, Jang JM, Ha HC, Lee HK, Shin IC, Kim JY, Kim HS, Kim DK

Ceramide metabolism is known to be an essential etiology for various diseases, such as atopic dermatitis and Gaucher disease. Glucosylceramide synthase (GCS) is a key enzyme for the synthesis of...
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Scorecard for early recognition of patients at high risk of delirium in emergency department

Kim JH, Do BS, Lee SB, Kim JH, Park SY

OBJECTIVE: This study was conducted to evaluate scorecards for early recognition of high-risk patients of delirium in the emergency department (ED). METHODS: Data from 399 consecutive patients aged 65 years or...
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Acceptance Test and Clinical Commissioning of CT Simulator

An HJ, Son J, Jin H, Sung J, Chun M

This study examined the clinical use of two newly installed computed tomography (CT) simulators in the Department of Radiation Oncology. The accreditation procedure was performed by the Korean Institute for...
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Segmental Analysis Trial of Volumetric Modulated Arc Therapy for Quality Assurance of Linear Accelerator

Rahman MM, Kim CH, Huh HD, Kim S

PURPOSE: Segmental analysis of volumetric modulated arc therapy (VMAT) is not clinically used for compositional error source evaluation. Instead, dose verification is routinely used for plan-specific quality assurance (QA). While...
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A clinical pilot study of jawbone mineral density measured by the newly developed dual-energy cone-beam computed tomography method compared to calibrated multislice computed tomography

Kim HJ, Kim JE, Choo J, Min J, Chang S, Lee SC, Pyun WB, Seo KS, Karm MH, Koo KT, Rhyu IC, Myoung H, Heo MS

PURPOSE: This clinical pilot study was performed to determine the effectiveness of dual-energy cone-beam computed tomography (DE-CBCT) in measuring bone mineral density (BMD). MATERIALS AND METHODS: The BMD values obtained using...
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Effects of energy level, reconstruction kernel, and tube rotation time on Hounsfield units of hydroxyapatite in virtual monochromatic images obtained with dual-energy CT

Jeong DK, Lee SS, Kim JE, Huh KH, Yi WJ, Heo MS, Choi SC

PURPOSE: This study was performed to investigate the effects of energy level, reconstruction kernel, and tube rotation time on Hounsfield unit (HU) values of hydroxyapatite (HA) in virtual monochromatic images...
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Accuracy of different electronic torque drivers: A comparative evaluation

Ko BD, Son K, Kang SH, Lee KB

PURPOSE: This study aims to evaluate the loosening torque on the implant fixture, and to assess the accuracy of difference electronic torque drivers. MATERIALS AND METHODS: Three electronic torque drivers were...
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Novel Prognostic Nomograms for Hepatocellular Carcinoma Patients with Microvascular Invasion: Experience from a Single Center

Xu L, Li L, Wang P, Zhang M, Zhang Y, Hao X, Yan L, Li B, Wen T, Xu M

BACKGROUND/AIMS: Microvascular invasion (MVI) is an established risk factor for hepatocellular carcinoma (HCC). However, prediction models that specifically focus on the individual prognoses of HCC patients with MVI is lacking. METHODS:...
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An Updated Nomogram for Predicting Invasiveness in Preoperative Ductal Carcinoma In Situ of the Breast

Kim S, Kim J, Park HS, Kim HY, Lee K, Lee J, Lee H, Kim JY, Kim SI, Cho YU, Park BW

PURPOSE: To validate and update a nomogram for predicting ductal carcinoma in situ (DCIS) upstaging in preoperative biopsy. MATERIALS AND METHODS: Medical records of 444 preoperative DCIS patients were evaluated and...
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Novel Prognostic Nomograms Based on Inflammation-Related Markers for Patients with Hepatocellular Carcinoma Underwent Hepatectomy

Wang Y, Sun K, Shen J, Li B, Kuang M, Cao Q, Peng S

PURPOSE: Hepatocellular carcinoma (HCC) is an aggressive disease with high recurrence rate. However, current staging systems were lack of predictive capacity for HCC recurrence. We aimed to develop prognostic nomograms...
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Nomogram Development and External Validation for Predicting the Risk of Lymph Node Metastasis in T1 Colorectal Cancer

Oh JR, Park B, Lee S, Han KS, Youk EG, Lee DH, Kim DS, Lee DS, Hong CW, Kim BC, Kim B, Kim MJ, Park SC, Sohn DK, Chang HJ, Oh JH

PURPOSE: Predicting lymph node metastasis (LNM) risk is crucial in determining further treatment strategies following endoscopic resection of T1 colorectal cancer (CRC). This study aimed to establish a new prediction...
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