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Mutagenic Assessment of Olmesartan Cilexetil by Bacterial Mutation Assay

Kim JW, Ahn I, Ryu SH, Jeon HR, Lee BS, Kim KB

  • KMID: 2317838
  • Toxicol Res.
  • 2013 Sep;29(3):217-219.
Hypertension is a serious health problem due to high frequency and concomitant other diseases including cardiovascular and renal dysfunction. Olmesartan cilexetil is a new antihypertensive drug associated with angiotensin II...
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Allergic Contact Dermatitis on the Periorbital Area: Report of Three Cases

Lee HB, Chung BY, Ahn I, Kim H, Park CW, Lee CH

  • KMID: 1455000
  • Korean J Dermatol.
  • 2010 May;48(5):429-434.
The use of ophthalmic drugs and contact lens solutions has increased and allergic contact dermatitis due to these agents has also recently increased. The first case was a 67-year-old female...
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Protein Backbone Torsion Angle-Based Structure Comparison and Secondary Structure Database Web Server

Jung S, Bae SE, Ahn I, Son HS

Structural information has been a major concern for biological and pharmaceutical studies for its intimate relationship to the function of a protein. Three-dimensional representation of the positions of protein atoms...
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The Current Trend of Avian Influenza Viruses in Bioinformatics Research

Ahn I, Son HS

OBJECTIVES: Since the first human infection from avian influenza was reported in Hong Kong in 1997, many Asian countries have confirmed outbreaks of highly pathogenic H5N1 avian influenza viruses....
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Epidemiological comparisons of codon usage patterns among HIV-1 isolates from Asia, Europe, Africa and the Americas

Ahn I, Son HS

  • KMID: 1115942
  • Exp Mol Med.
  • 2006 Dec;38(6):643-651.
To investigate the genomic properties of HIV-1, we collected 3,081 sequences from the HIV Sequence Database. The sequences were categorized according to sampling region, country, year, subtype, gene name, and...
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Risk Factors for Depression of Patients with Tuberculosis in Tuberculosis Specialty Hospital

Wang JH, Park CS, Kim BJ, Lee CS, Cha B, Lee SJ, Lee D, Seo JY, Ahn I, Chul BJ, Kang HS, Moon SH

OBJECTIVES: This study aimed to investigate the risk factors of depression for patients with tuberculosis(TB). METHODS: A total of 57 patients with TB were recruited. All participants completed the Becks Depression...
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Genetic Association between Eotaxin Genes and Asthma and Its Relationship to Birth Season in Korean Children

Ahn I, Bae SE, Kim JH, Son BK, Son HS, Cho SI

  • KMID: 1450881
  • Genomics Inform.
  • 2011 Mar;9(1):12-18.
Asthma is a chronic disease associated with airway constriction due to inflammation caused by eosinophils, mast cells, and T lymphocytes, leading to serious chronic illness in children. The eotaxin gene...
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Comparative study of synonymous codon usage variations between the nucleocapsid and spike genes of coronavirus, and C-type lectin domain genes of human and mouse

Ahn I, Jeong BJ, Son HS

Coronaviruses (CoVs) are single-stranded RNA viruses which contain the largest RNA genomes, and severe acute respiratory syndrome coronavirus (SARS-CoV), a newly found group 2 CoV, emerged as infectious disease with...
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Comparative study of codon substitution patterns in foot-and-mouth disease virus (serotype O)

Ahn I, Bae SE, Son HS

We compared genetic variations in the VP1 gene of foot-and-mouth disease viruses (FMDVs) isolated since 2000 from various region of the world. We analyzed relative synonymous codon usage (RSCU) and...
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Correlations Between the Incidence of National Notifiable Infectious Diseases and Public Open Data, Including Meteorological Factors and Medical Facility Resources

Jang JH, Lee JH, Je MK, Cho MJ, Bae YM, Son HS, Ahn I

OBJECTIVES: This study was performed to investigate the relationship between the incidence of national notifiable infectious diseases (NNIDs) and meteorological factors, air pollution levels, and hospital resources in Korea. METHODS: We...
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Comparative bioinformatics analysis of prion proteins isolated from reptile, rodent, ruminant, and human species

Ahn I, Son HS

  • KMID: 1091071
  • Exp Mol Med.
  • 2007 Dec;39(6):769-777.
Prion proteins (PrPs) are infectious pathogens that cause a group of invariably fatal, neurodegenerative diseases, including Creutzfeldt-Jakob disease, by means of an entirely novel mechanism. They are produced by various...
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Discriminant analysis of prion sequences for prediction of susceptibility

Lee JH, Bae SE, Jung S, Ahn I, Son HS

  • KMID: 2154267
  • Exp Mol Med.
  • 2013 Oct;45(10):e48.
Prion diseases, including ovine scrapie, bovine spongiform encephalopathy (BSE), human kuru and Creutzfeldt-Jakob disease (CJD), originate from a conformational change of the normal cellular prion protein (PrPC) into abnormal protease-resistant...
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