Yonsei Med J.  2008 Oct;49(5):698-704. 10.3349/ymj.2008.49.5.698.

The Behcet't Disease Quality of Life: Reliability and Validity of the Korean Version

• Yi SW
• Kim JH
• Lim KY
• Bang D
• Lee S
• Lee ES

• KMID: 2158186
• DOI: http://doi.org/10.3349/ymj.2008.49.5.698

Abstract

PURPOSE: The Behcet's Disease Quality of Life (BD-QoL) is a BD-specific measure developed in the UK. The aim of this study was to adapt the BD-QoL for use in Korea.
PATIENTS AND METHODS
The translation was based on the guidelines for cross-cultural adaptation. A total of 201 Korean patients with BD participated in this study. To evaluate the psychometric properties, internal consistency and test-retest reliability were used. Factor analysis was performed to examine the construct validity. To provide further evidence for validity, the correlation of BD-QoL with the Clinical Activity Form for Korean Patients with BD (BDCAF-K) and the Center for Epidemiologic Studies-Depression (CES-D) scales was assessed.
RESULTS
The Korean version had high internal consistency (Cronbach's alpha, 0.93) and test-retest reliability (r = 0.835). Factor analysis of the questionnaire revealed one interpretable factor as a general health-related quality of life factor. The Korean version significantly correlated with scores of CES-D (r = 0.749, p = 0.000), self-rating scale of well-being over the past 28 days (r = 0.446, p = 0.000), and BDCAF-K score (r = 0.502, p = 0.000).
CONCLUSION
Adaptation of the BD-QoL for use in Korea was successful. Together with the BDCAF-K, it may be a valuable tool for assessing the influence of interventions in BD patients and outcome in clinical trials.

Keyword

Adaptation; Behcet's disease; quality of life; reliability; validity

MeSH Terms

Adolescent
Adult
Aged
Behcet Syndrome/diagnosis/*psychology/therapy
Child
Cultural Characteristics
Female
Humans
Korea
Language
Male
Middle Aged
*Quality of Life
Questionnaires/*standards

Figure

• 

  Fig. 1 Scree plot of eigenvalues obtained in the factor analysis plotted against their associated components.

Reference

1. Suzuki Kurokawa M, Suzuki N. Behçet's disease. Clin Exp Med. 2004. 4:10–20.

2. Alpsoy E, Zouboulis CC, Ehrlich GE. Mucocutaneous lesions of Behçet's disease. Yonsei Med J. 2007. 48:573–585.

3. Gilworth G, Chamberlain MA, Bhakta B, Haskard D, Silman A, Tennant A. Development of the BD-QoL: a quality of life measure specificto Behçet's disease. J Rheumatol. 2004. 31:931–937.

4. Bhakta BB, Brennan P, James TE, Chamberlain MA, Noble BA, Silman AJ. Behçet's disease: evaluation of a new instrument to measure clinical activity. Rheumatology (Oxford). 1999. 38:728–733.

5. Emery P, Kosinski M, Li T, Martin M, Williams GR, Becker JC, et al. Treatment of rheumatoid arthritis patients with abatacept and methotrexate significantly improved health-related quality of life. J Rheumatol. 2006. 33:681–689.

6. Blackford S, Finlay AY, Roberts DL. Quality of life in Behçet's syndrome: 335 patients surveyed. Br J Dermatol. 1997. 136:293.

7. Bodur H, Borman P, Özdemir Y, Atan Ç, Kural G. Quality of life and life satisfaction in patients with Behçet's disease: relationship with disease activity. Clin Rheumatol. 2006. 25:329–333.

8. Gur A, Sarac AJ, Burkan YK, Nas K, Cevik R. Arthropathy, quality of life, depression, and anxiety in Behçet's disease: relationship between arthritis and these factors. Clin Rheumatol. 2006. 25:524–531.

9. International Study Group for Behçet's Disease (ISGBD). Criteria for diagnosis of Behçet's disease. Lancet. 1990. 335:1078–1080.

10. Beaton DE, Bombardier C, Guillemin F, Ferraz MB. Guidelines for the process of cross-cultural adaptation of self-report measures. Spine. 2000. 25:3186–3191.

11. Lee ES, Kim HS, Bang D, Yu HG, Chung H, Shin DH, et al. Development of clinical activity form for Korean patients with Behçet's disease. Adv Exp Med Biol. 2003. 528:153–156.

12. Cho MJ, Kim KH. Use of the Center for Epidemiologic Studies Depression (CES-D) Scale in Korea. J Nerv Ment Dis. 1998. 186:304–310.

13. Hubley AM, Russell LB, Palepu A. Injection Drug Use Quality of Life Scale (IDUQOL): a validation study. Health Qual Life Outcomes. 2005. 3:43.

14. DeVellis RF. DeVellis RF, editor. Factor analysis. Scale development: Theory and applications (applied Social Research Methods). 2003. 2nd ed. Thousand Oaks: Sage Publications;102–137.

15. Russell DW. In search of underlying dimensions: The use (and abuse) of factor analysis in personality and social psychology bulletin. Pers Soc Psychol Bull. 2002. 28:1629–1646.

16. Weissman MM, Bland R, Joyce PR, Newman S, Wells JE, Wittchen HU. Sex differences in rates of depression: cross-national perspectives. J Affect Disord. 1993. 29:77–84.

17. Mumcu G, Inanc N, Ergun T, Ikiz K, Gunes M, Islek U, et al. Oral health related quality of life is affected by disease activity in Behçet's disease. Oral Dis. 2006. 12:145–151.