Ann Dermatol.  2011 Oct;23(Suppl 2):S179-S181. 10.5021/ad.2011.23.S2.S179.

Vulvar Skin Metastasis of Lung Squamous Cell Carcinoma

• Sim JH
• Kim JE
• Lee SH
• Cho MK
• Lee JS
• Lee SY

• KMID: 2156783
• DOI: http://doi.org/10.5021/ad.2011.23.S2.S179

Abstract

In this study, we examined a case where lung cancer metastasized to the vulvar area. A 79-year-old woman that was a heavy smoker was referred to our department with a short (two-week) history of dyspnea, and with a painful nodule on her right labium majora, which she had noticed almost three years earlier. Histopathologically, the specimen appeared as a poorly differentiated squamous cell carcinoma. The chest X-ray, chest computerized tomography scan, and percutaneous transthoracic needle biopsy via bronchoscopy revealed squamous cell carcinoma in the right upper lobe of the lung. Based on these clinical and histopathological findings, we concluded that her condition was skin metastasis at the right labium majora from the lung cancer, which occurs very rarely.

Keyword

Lung cancer; Metastasis; Skin cancer

MeSH Terms

Aged
Biopsy, Needle
Bronchoscopy
Carcinoma, Squamous Cell
Dyspnea
Female
Humans
Lung
Lung Neoplasms
Neoplasm Metastasis
Skin
Skin Neoplasms
Thorax

Figure

• 

  Fig. 1 An erythematous nodule 3×3 cm in size on the right labia majora and the adjacent skin in a 79-year-old woman.

• 

  Fig. 2 (A) Atypical cells are present throughout the dermis (H&E, ×40). (B) Poorly differentiated atypical tumor cells (H&E, ×200).

• 

  Fig. 3 CT scan showing an ill-defined 7.5×7 cm round hypodense mass in the right upper lobe of the lung (asterisk).

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