J Gynecol Oncol.  2009 Dec;20(4):254-256. 10.3802/jgo.2009.20.4.254.

Pregnancy following vulvar squamous cell carcinoma: a report of two cases

Affiliations
  • 1Department of Gynaecological Oncology, Royal Hallamshire Hospital, Sheffield, UK. palmer006@btinternet.com

Abstract

Pregnancy following squamous cell carcinoma of the vulvar is rare. Its rarity is reflected by a paucity of cases reported in the literature. We report two cases of pregnancy following diagnosis and treatment for vulvar squamous cell carcinoma, and review eleven prior reported cases. In successfully treated vulvar cancer subsequent pregnancy is not shown to increase the risk of disease recurrence, and there appears to be no deleterious effects during the antenatal period. It is possible, when considering prior reports, that prior vulvectomy may increase the likelihood of delivery by caesarean section, though modifications in the surgical management of vulvar carcinoma may have decreased this risk.

Keyword

Vulvar cancer; Squamous cell carcinoma; Radical vulvectomy; Pregnancy

MeSH Terms

Carcinoma, Squamous Cell
Cesarean Section
Female
Pregnancy
Recurrence
Vulvar Neoplasms

Reference

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5. Collins JH, Birch HW, Pailet M, Avent JK. Pregnancy and delivery following extensive vulvectomy. Am J Obstet Gynecol. 1960. 80:167–171.
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8. Hacker NF, Van der Velden J. Conservative management of early vulvar cancer. Cancer. 1993. 71:4 suppl. 1673–1677.
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