Anesth Pain Med.
2015 Apr;10(2):124-127. 10.17085/apm.2015.10.2.124.
Effectiveness of sugammadex in reversing prolonged neuromuscular block in a patient with acquired immune deficiency syndrome (AIDS) taking streptomycin: A case report
- Affiliations
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- 1Department of Anesthesiology and Pain Medicine, National Medical Center, Seoul, Korea. facharzt@gmail.com
- 2Department of Anesthesiology and Pain Medicine, Hanyang University Hospital, Seoul, Korea.
- KMID: 2148046
- DOI: http://doi.org/10.17085/apm.2015.10.2.124
Abstract
- The duration of the effect of muscle relaxants is extended in patients with acquired immunodeficiency syndrome (AIDS); however, a specific mechanism for this effect has not yet been discovered. In addition, streptomycin is known to prolong the action of muscle relaxants by blocking activity at neuromuscular junctions. Here, we report the case of patient with AIDS taking streptomycin for pulmonary tuberculosis for which sugammadex was effective in reversing prolonged paralysis induced by rocuronium and vecuronium for video-assisted thoracoscopic surgery (VATS) lung wedge resection.
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