Anesth Pain Med.  2015 Jul;10(3):192-195. 10.17085/apm.2015.10.3.192.

The relationship between the serum lactate level and in-hospital mortality after decompressive craniectomy in traumatic brain Injury

• Jung WS
• Lee D
• Chang YJ
• Park CK
• Jo YY

• KMID: 2148030
• DOI: http://doi.org/10.17085/apm.2015.10.3.192

Abstract

BACKGROUND
The patients with traumatic brain injury showed ischemia due to increased intracranial pressure. This study evaluated the relationship of pre-anesthetic serum lactate level with in-hospital mortality.
METHODS
The archived medical records of 121 patients were retrospectively reviewed. Demographics and preoperative serum lactate level were analyzed.
RESULTS
Of the 121 patients, 32 patients expired in the hospital after decompressive craniectomy. Preoperative serum lactate levels were 3.2 +/- 2.2 mmol/L in the survivors and 5.4 +/- 3.0 mmol/L in the dead (P = 0.001), and the receiver operating characteristic curve revealed that a cut off value of 3.60 mmol/L was reasonable for predicting mortality.
CONCLUSIONS
Preoperative serum lactate level is highly correlated with in-hospital mortality after decompressive craniectomy in traumatic brain injury.

Keyword

Mortality; Serum lactate; Traumatic brain injury

MeSH Terms

Brain Injuries*
Decompressive Craniectomy*
Demography
Hospital Mortality*
Humans
Intracranial Pressure
Ischemia
Lactic Acid*
Medical Records
Mortality
Retrospective Studies
ROC Curve
Survivors
Lactic Acid