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Platelet-Derived Growth Factor Receptor-α Subunit Targeting Suppresses Metastasis in Advanced Thyroid Cancer In Vitro and In Vivo

Lin CL, Tsai ML, Chen Yh, Liu WN, Lin CY, Hsu KW, Huang CY, Chang YJ, Wei PL, Chen SH, Huang LC, Lee CH

Thyroid cancer is the most common endocrine malignancy. Patients with well-differentiated thyroid cancers, such as papillary and follicular cancers, have a favorable prognosis. However, poorly differentiated thyroid cancers, such as...
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A Qualitative Study on Discharge Planning Needs for Cancer Patients

Kim KO, Jung SY, Chang YJ

Purpose: The purpose of this study was to identify the unmet needs experienced by patients discharged after cancer surgery in order to develop a systematic discharge plan. Methods: In-depth interviews...
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Second Primary Ovarian Epithelial, Fallopian Tube, and Primary Peritoneal Cancers after Breast Cancer Diagnosis: Korea Central Cancer Registry

Ha HI, Lee EG, Lim J, Jung SY, Chang YJ, Won YJ, Lim MC

Purpose A prior history of breast cancer is a risk factor for the subsequent development of primary peritoneal, epithelial ovarian, and fallopian tubal (POFT) cancers. This study aimed to estimate...
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Head and neck reconstruction using free flaps: a 30-year medical record review

Suh JM, Chung CH, Chang YJ

Background: The free flap surgical method is useful for the reconstruction of head and neck defects. This study retrospectively analyzed the results of head and neck reconstructions using various types...
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L1 Slope as an Indicator of Thoracolumbar Sagittal Balance in Osteoporotic Vertebral Fractures

Lee SM, Park JH, Chang YJ, Shim SW, Baek SN, Choi YS

Objectives: To evaluate the association between L1 slope and thoracolumbar spinal parameters of sagittal balance in cases of osteoporotic vertebral fracture. Summary of Literature Review: Recently, interest has emerged in the...
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Clinical Practice Guideline for Care in the Last Days of Life

Shin J, Chang YJ, Park SJ, Choi JY, Kim SH, Choi YS, Kim NH, Yum HK, Nam EM, Park MH, Moon N, Moon JY, Kang HT, Kang JH, Park JM, Lee CW, Kim SY, Lee EJ, Koh SJ, Kim Y, Agnes Cho M, Song Y, Shim JY

A clinical practice guideline for patients in the dying process in general wards and their families, developed through an evidence-based process, is presented herein. The purpose of this guideline is...
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Effects of different sugammadex doses on the train of four ratio recovery progression during rocuronium induced neuromuscular blockade in the rat phrenic nerve hemidiaphragm

Kim YB, Choi JM, Chang YJ, Choi HR, In J, Yang HS

Background: In this study, we used an ex-vivo model to investigate the recovery pattern of both the train-of-four (TOF) ratio and first twitch tension of TOF (T1), and determined their...
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Primary amelanotic melanoma of the mandibulargingiva

Kim BJ, Kim HS, Chang YJ, Kwon KH, Cho SJ

Oral mucosal melanoma is a very rare type of malignant melanoma, the characteristics of which differ from those of cutaneous melanoma. Primary amelanotic melanoma of the mandibular gingiva, which can invade the...
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Klebsiella pneumoniae necrotizing fasciitis on theupper lip in a patient with uncontrolled diabetes

Kim HS, Chang YJ, Chung CH

A 60-year-old woman with a history of diabetes mellitus and chronic renal failure was admitted to the hospital with severe pain in the upper lip, which began 4 days prior to...
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in vivo multiplex gene targeting with Streptococcus pyogens and Campylobacter jejuni Cas9 for pancreatic cancer modeling in wildtype animal

Chang YJ, Bae J, Zhao Y, Lee G, Han J, Lee YH, Koo OJ, Seo S, Choi YK, Yeom SC

Pancreatic ductal adenocarcinoma is a lethal cancer type that is associated with multiple gene mutations in somatic cells. Genetically engineered mouse is hardly applicable for developing a pancreatic cancer model,...
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Salvaging a Severely Burned Ankle Using Arthrodesis and Anterolateral Thigh Free Flap

Suh JM, Chang YJ, Chung CH, Kim GL

A 72-year-old male patient without underlying diseases presented with a flame burn injury on the fibula and talus of the ankle joint and soft tissue around the posterior lower leg....
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Free-flap reconstruction in recurrent head and neck cancer: A retrospective review of 124 cases

Kim HS, Chung CH, Chang YJ

Background: Free-flap reconstruction for recurrent head and neck cancer may be challenging depending on the previous treatments, those are, chemotherapy, radiotherapy, and surgery, including neck dissection or free tissue transfer....
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Views on Precision Medicine among Health Professionals in Korea: A Mixed Methods Study

Cho HN, Shin SY, Hwangbo B, Chang YJ, Cho J, Kong SY, Choi KS, Lee ES

This study aimed to investigate awareness, attitudes, and perspectives on precision medicine among health professionals in Korea and to identify issues that need to be addressed before implementing precision medicine....
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Long-Term Survival after Wide Resection of Malignant Fibrous Histiocytoma of the Chest Wall

Shin JW, Chang YJ, Cho DG, Choi SY

Primary malignant fibrous histiocytoma (MFH) of the chest wall is extremely rare and is characterized by aggressive features, including a high incidence of local recurrence and distant metastasis. Surgical resection...
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Prognostic Value of Post-diagnosis Health-Related Quality of Life for Overall Survival in Breast Cancer: Findings from a 10-Year Prospective Cohort in Korea

Mai TT, Choi JH, Lee MK, Chang YJ, Jung SY, Cho H, Lee ES

PURPOSE: We aimed to evaluate health-related quality of life (HRQOL) at 1-year post-diagnosis in breast cancer (BC) patients and its association with overall survival using data from the National Cancer...
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Consensus guidelines for the definition of the end stage of disease and last days of life and criteria for medical judgment

Lee SM, Kim SJ, Choi YS, Heo DS, Baik S, Choi BM, Kim D, Moon JY, Park SY, Chang YJ, Hwang IC, Kwon JH, Kim SH, Kim YJ, Park J, Ahn HJ, Lee HW, Kwon I, Kim DK, Kim OJ, Yoo SH, Cheong YS, Koh Y

In Korea, the Hospice, Palliative Care, and Life-sustaining Treatment Decision-making Act was enacted in February 2016 in order to ensure that the patient's self-determination in end-of-life care processes is respected....
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An 8-Week Low-Intensity Progressive Cycling Training Improves Motor Functions in Patients with Early-Stage Parkinson's Disease

Chang HC, Lu CS, Chiou WD, Chen CC, Weng YH, Chang YJ

BACKGROUND AND PURPOSE: The effects of high-intensity cycling as an adjuvant therapy for early-stage Parkinson's disease (PD) were highlighted recently. However, patients experience difficulties in maintaining these cycling training programs....
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Effects of adenosine receptor agonist on the rocuronium-induced neuromuscular block and sugammadex-induced recovery

Kim YB, Lee S, Choi HR, In J, Chang YJ, Kim HJ, Ro YJ, Yang HS

BACKGROUND: Several types of receptors are found at neuromuscular presynaptic membranes. Presynaptic inhibitory A1 and facilitatory A2A receptors mediate different modulatory functions on acetylcholine release. This study investigated whether adenosine...
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Factors Related with Utilizing Hospice Palliative Care Unit among Terminal Cancer Patients in Korea between 2010 and 2014: a Single Institution Study

Park SJ, Nam EJ, Chang YJ, Lee YJ, Jho HJ

BACKGROUND: Establishing and designating specialized hospice palliative care units (HPCUs) has been an important part of national policy to promote hospice palliative care in Korea in the recent decade. However,...
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Erratum: Effect of needle approach to the axillary artery on transarterial axillary brachial plexus block quality

Chang YJ, Lee DC, Oh YJ, Ha DH, Lee MG

Figure 1 was printed with incorrect text. In the Figure, “Radial artery” should be corrected to “Axillary artery.”
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