Korean J Hematol.  2002 Nov;37(4):302-306.

Successful Treatment of Non-Hodgkin's Lymphoma during Pregnancy and Long-term Follow-up of a Child born to the Mother

Affiliations
  • 1Department of Internal Medicine, Gyeong-Sang National University College of Medicine, Jinju, Korea. jonglee@nongae.gsnu.ac.kr
  • 2Department of Pediatrics, Gyeong-Sang National University College of Medicine, Jinju, Korea.
  • 3Department of Pathology, Gyeong-Sang National University College of Medicine, Jinju, Korea.

Abstract

The occurrence of Non-Hodgkin's lymphoma (NHL) during pregnancy is rare. The optimal management of NHL during pregnancy requires special considerations. Because of their rapid progression, women with aggressive NHL should receive standard chemotherapy despite the potential risk to the developing fetus. We experienced a case of 30-year-old pregnant woman diagnosed as a diffuse large B cell NHL at 28 weeks of gestation, who was taken 4 cycles of CHOP combination chemotherapy and delivered a male baby weighing 2660g at 39 weeks of gestation. Following delivery, she received additional 3 cycles of chemotherapy with 4500cGy of radiotherapy on the neck. While she has been in complete remission of NHL over 6 years, her baby have developed mild developmental retardation.

Keyword

Non-Hodgkin's lymphoma; Pregnancy; Chemotherapy

MeSH Terms

Adult
Child*
Drug Therapy
Drug Therapy, Combination
Female
Fetus
Follow-Up Studies*
Humans
Lymphoma, Non-Hodgkin*
Male
Mothers*
Neck
Pregnancy*
Pregnant Women
Radiotherapy
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