Korean J Med.  1999 Apr;56(4):537-541.

A Case of Polymyositis Preceded by Bronchiolitis Obliterans with Organizing Pneumonia(BOOP)

Affiliations
  • 1Department of Internal Medicine, Kyung Hee University College of Medicine, Seoul, Korea.

Abstract

Polymyositis is a inflammatory connective tissue disorder of unknown etiology involving predominantly skeletal muscle, characterized by progressive symmetrical proximal muscle weakness, elevated serum muscle associated enzymes, characteristic pattern of electromyography, mononuclear cell infiltration in muscle, and skin lesions in dermatomyositis. Interstitial lung disease in association with polymyositis occurs in 5~10% of cases, with generally a poor prognosis and its subclassification may be a useful predictor of survival. We have experienced a case of polymyositis associated with bronchiolitis obliterans with organizing pneumonia (BOOP). The patient was a 54 year-old woman presented with progressive weakness of both lower extremity and weight loss during 6 months. She had been diagnosed as BOOP by transbronchial lung biopsy 2 years ago. She had typical symptoms, physical signs and elevated serum muscle associated enzymes with characteristic findings of myositis on electromyography and muscle biopsy. Her chest roentgenogram showed slightly improvement of underlying BOOP as compared with that of 2 years ago. Because wound infection was developed at the skin biopsy site, steroid was not used. She finally expired due to sudden cardiopulmonary arrest.

Keyword

Polymyositis; Bronchiolitis Obliterans with Organizing Pneumonia(BOOP)

MeSH Terms

Biopsy
Bronchiolitis Obliterans*
Bronchiolitis*
Connective Tissue
Cryptogenic Organizing Pneumonia
Dermatomyositis
Electromyography
Female
Heart Arrest
Humans
Lower Extremity
Lung
Lung Diseases, Interstitial
Middle Aged
Muscle Weakness
Muscle, Skeletal
Myositis
Pneumonia
Polymyositis*
Prognosis
Skin
Thorax
Weight Loss
Wound Infection
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