Korean J Med.  2001 Jul;61(1):86-90.

A case of primary antiphospholipid syndrome with renal microangiopathy

Affiliations
  • 1Department of Medicine and Diagnostic Pathology, Sungkyunkwan University School of Medicine, Seoul, Korea.
  • 2Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.

Abstract

Antiphospholipid syndrome is a disease that has continuous high titer of antibodies directed against either phospholipids or plasma proteins bound to anionic phospholipids in serum and shows a variety of clinical manifestations including recurrent venous and arterial thrombosis, recurrent fetal losses, livedo reticularis and thrombocytopenia. Because thrombosis may develop in any vessel, clinical manifestations are variable. Renal microangiopathy has been reported in antiphospholipid syndrome associated with systemic lupus erythematosus and rarely reported in primary antiophospholipid syndrome. But there was no case report of antiphospholipid syndrome accompanied by renal microangiopathy in Korea. Recently, we experienced a 25 years old male patient who had primary antiphospholipid syndrome with intrarenal thrombotic microangiopathy and IgA nephropathy. So, we report this case with review of relevant literature.

Keyword

Antiphospholipid syndrome; Antiphospholipid antbody; Renal microangiopathy

MeSH Terms

Adult
Antibodies
Antiphospholipid Syndrome*
Blood Proteins
Glomerulonephritis, IGA
Humans
Korea
Livedo Reticularis
Lupus Erythematosus, Systemic
Male
Phospholipids
Thrombocytopenia
Thrombosis
Thrombotic Microangiopathies
Antibodies
Blood Proteins
Phospholipids
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