Korean J Med.
2001 Jul;61(1):86-90.
A case of primary antiphospholipid syndrome with renal microangiopathy
- Affiliations
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- 1Department of Medicine and Diagnostic Pathology, Sungkyunkwan University School of Medicine, Seoul, Korea.
- 2Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.
Abstract
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Antiphospholipid syndrome is a disease that has continuous high titer of antibodies directed against either phospholipids or plasma proteins bound to anionic phospholipids in serum and shows a variety of clinical manifestations including recurrent venous and arterial thrombosis, recurrent fetal losses, livedo reticularis and thrombocytopenia. Because thrombosis may develop in any vessel, clinical manifestations are variable. Renal microangiopathy has been reported in antiphospholipid syndrome associated with systemic lupus erythematosus and rarely reported in primary antiophospholipid syndrome. But there was no case report of antiphospholipid syndrome accompanied by renal microangiopathy in Korea. Recently, we experienced a 25 years old male patient who had primary antiphospholipid syndrome with intrarenal thrombotic microangiopathy and IgA nephropathy. So, we report this case with review of relevant literature.