Korean J Nephrol.
2011 Nov;30(6):656-660.
A Case of Immunoglobulin G4-Related Tubulointerstitial Nephritis with Extrarenal Involvement
- Affiliations
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- 1Department of Internal Medicine, Pusan National University Hospital, Busan, Republic of Korea. shsong@pusan.ac.kr
- 2Biomedical Research Institute, Pusan National University Hospital, Busan, Republic of Korea.
Abstract
- Immunoglobulin G4-related sclerosing disease is a novel clinicopathological disease entity known to involve various organs including the pancreas, bile ducts, gall bladder, retroperitoneum, kidney, salivary gland, lung and prostate. The most common organ involved is the pancreas and cases without pancreatic involvement are uncommon. Positive response to steroids is an important characteristic of this disease and this enables early diagnosis, which is required for good prognosis. We demonstrate a case of immunoglobulin G4-related tubulointerstitial nephritis in a 59-year-old male accompanied by sclerosing cholangitis and sialadenitis without any evidence of pancreatic infiltration. The patient was treated with prednisolone and was fully recovered in 6 months.
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