J Korean Diabetes.  2011 Jun;12(2):80-82. 10.4093/jkd.2011.12.2.80.

Pathogenesis of the Diabetic Foot Disease

Affiliations
  • 1Department of Internal Medicine, Hallym University Medical Center, Kangdong Sacred Heart Hospital, Seoul, Korea. dm@hallym.or.kr

Abstract

Diabetic foot disease is a major health problem affecting people with diabetes in developed countries, as well as in many developing countries. In people with diabetes the lifetime risk of developing diabetic foot ulcer is about 25%, and this risk may be increased in elderly people with type 2 diabetes. Although the prevalence and severity of diabetic foot disease varies in different regions, peripheral neuropathy is the common pathway leading to ulceration or diabetic foot disease across regions. The pathogenesis and related factors of diabetic foot disease are briefly described in this report.

Keyword

Diabetic foot; Pathogenesis; Neuropathy; Peripheral arterial disease

MeSH Terms

Aged
Developed Countries
Developing Countries
Diabetic Foot
Humans
Peripheral Arterial Disease
Peripheral Nervous System Diseases
Prevalence
Ulcer
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