Tuberc Respir Dis.  2004 Mar;56(3):315-320. 10.4046/trd.2004.56.3.315.

A Case of Drug Induced Interstitial Pneumonitis by Gemcitabine

Affiliations
  • 1Department of Internal Medicine, Inje University, Medical School, Korea.
  • 2Department of Radiology, Inje University, Medical School, Korea.

Abstract

Gemcitabine is an effective newly developed chemotherapeutic agent, which is increasingly being used to treat non-small cell lung, ovarian and breast cancers. Pulmonary toxicity is usually self-limiting mild dyspnea, bronchospasm, but severe pulmonary toxicity is rarely reported. Herein, we report drug induced interstitial lung disease associated with gemcitabine treatment. High resolution computerized tomogram (HRCT) showed an increased ground glass opacity and thickened septal lines. The patient showed a rapid good response with prednisolone treatment.

Keyword

Gemcitabine; Pulmonary infiltrates; Corticosteroid therapy; Capillary leak syndrome

MeSH Terms

Breast
Bronchial Spasm
Capillary Leak Syndrome
Dyspnea
Glass
Humans
Lung
Lung Diseases, Interstitial*
Prednisolone
Prednisolone
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