Asia Pac Allergy.  2015 Oct;5(4):234-236. 10.5415/apallergy.2015.5.4.234.

Application of hypersensitivity skin testing in chemotherapy-induced pneumonitis

• Kuo JC
• Hawkins CA
• Yip D

• KMID: 2397041
• DOI: http://doi.org/10.5415/apallergy.2015.5.4.234

Abstract

Skin testing has been utilised to determine the culprit allergenic agent in drug reactions. Its application in the setting of hypersensitivity reaction relating to combination chemotherapeutic regimens may help identify the causative drug, allowing drug that is safe to be continued and avoiding limiting treatment options for patients. We report what we believe to be the first published case of hypersensitivity skin testing for gemcitabine-induced pneumonitis in a patient with metastatic leiomyosarcoma and another case of docetaxel-induced pneumonitis in a patient with metastatic HER2-positive breast cancer.

Keyword

Skin Tests; Lung Diseases, Interstitial; Antineoplastic Agents; Antibodies, Monoclonal; Hypersensitivity

MeSH Terms

Antibodies, Monoclonal
Antineoplastic Agents
Breast Neoplasms
Humans
Hypersensitivity*
Leiomyosarcoma
Lung Diseases, Interstitial
Pneumonia*
Skin Tests*
Skin*
Antibodies, Monoclonal
Antineoplastic Agents

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