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Clinical Scales for Diabetic Neuropathy and Chemotherapy-induced Neuropathy

Oh J

Diabetic neuropathy and chemotherapy-induced peripheral neuropathy are complex disorders affecting different nerve fiber group and remain as major source of morbidity and decreased quality of life of the patients. Given...
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Effect of Combining EGFR Tyrosine Kinase Inhibitors and Cytotoxic Agents on Cholangiocarcinoma Cells

Boonsri B, Yacqub-Usman K, Thintharua P, Myint KZ, Sae-Lao T, Collier P, Suriyonplengsaeng C, Larbcharoensub N, Balasubramanian B, Venkatraman S, Egbuniwe IU, Gomez D, Mukherjee A, Kumkate S, Janvilisri T, Zaitoun AM, Kuakpaetoon T, Tohtong R, Grabowska AM, Bates DO, Wongprasert K

Purpose The potential of members of the epidermal growth factor receptor (ErbB) family as drug targets in cholangiocarcinoma (CCA) has not been extensively addressed. Although phase III clinical trials showed...
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Factors Influencing Compliance with Safe Handling of Antineoplastic Agents Among Clinical Nurses

Lee H, Song JE, Ahn JA, Boo S

Purpose: This study aimed to investigate the levels of compliance with safe handling of antineoplastic agents, time pressure, knowledge of safe handling of antineoplastic agents, and workplace safety climate, and...
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Usefulness of cyclic thermal therapy and red blood cell scintigraphy in patients with chemotherapy-induced peripheral neuropathy

Kim M, Kim EM, Oh PS, Lim ST, Sohn MH, Song EK, Park KU, Kim JY, Won KS, Jeong HJ

Background: Pharmacological and non-pharmacological therapies have been used to treat patients with chemotherapy-induced peripheral neuropathy (CIPN). However, the effect of therapies in cancer patients has yet to be investigated comprehensively....
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Determinants of neoadjuvant chemotherapy use in muscle-invasive bladder cancer

Carvalho FL, Zeymo A, Egan J, Kelly CH, Zheng C, Lynch JH, Hwang J, Stamatakis L, Krasnow RE, Kowalczyk KJ

Purpose: Cisplatin-based neoadjuvant chemotherapy (NAC) followed by radical cystectomy (RC) is standard of care for muscleinvasive bladder cancer (MIBC). However, NAC is used in less than 20% of patients with...
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Impressive effect of cisplatin monotherapy on a patient with heavily pretreated triple-negative breast cancer with poor performance

Baek DW, Park JY, Lee SJ, Chae YS

Systemic therapy for metastatic triple-negative breast cancer (TNBC) still remains challenging because there are no targeted agents or endocrine therapies currently available. The present case report documents the successful use...
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Baseline Serum Interleukin-6 Levels Predict the Response of Patients with Advanced Non-small Cell Lung Cancer to PD-1/PD-L1 Inhibitors

Kang DH, Park CK, Chung C, Oh IJ, Kim YC, Park D, Kim J, Kwon GC, Kwon I, Sun P, Shin EC, Lee JE

Although various studies on predictive markers in the use of PD-1/PD-L1 inhibitors are in progress, only PD-L1 expression levels in tumor tissues are currently used. In the present study, we...
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The Use of Gonadotropin-Releasing Hormone Agonist Does Not Affect the Development of Cardiovascular Disease in Prostate Cancer Patients: a Nationwide Population-Based Cohort Study

Shim M, Bang WJ, Oh CY, Lee YS, Jeon SS, Ahn H, Ju YS, Cho JS

BACKGROUND: The objective of this study was to investigate whether androgen deprivation therapy (ADT) with gonadotropin-releasing hormone agonist (GnRHa) in prostate cancer (Pca) patients is associated with cardiovascular disease in...
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Recent Advances in the Development of TGF-β Signaling Inhibitors for Anticancer Therapy

Lee HJ

TGF-β is a multifunctional cytokine that plays an important role in both physiologic and pathologic processes, including cancer. Importantly, TGF-β has a dual role in tumorigenesis, acting as a tumor...
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Effect of Podophyllotoxin Conjugated Stearic Acid Grafted Chitosan Oligosaccharide Micelle on Human Glioma Cells

Wang GH, Shen HP, Huang X, Jiang XH, Jin CS, Chu ZM

Objective : To study the physiochemical characteristics of podophyllotoxin (PPT) conjugated stearic acid grafted chitosan oligosaccharide micelle (PPT-CSO-SA), and evaluate the ability of the potential antineoplastic effects against glioma cells. Methods...
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Change in Estradiol Levels among Premenopausal Patients with Breast Cancer Treated Using Leuprolide Acetate 11.25 Milligrams 3-Month Depot and Tamoxifen

Lee Yj, Wu ZY, Kim Hj, Lee JW, Chung IY, Kim J, Lee SB, Son BH, Kim SB, Jung JH, Gong G, Ahn SH, Ko B

The combination of luteinizing hormone-releasing hormone analogs (LHRHa) with tamoxifen is used as a standard postoperative adjuvant therapy in patients with hormone receptor-positive/premenopausal breast cancer. Long-acting LHRHa formulations offer advantages...
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Optimal Management of Chemotherapy-related Adverse Events

Jung MK

This review article deals with the optimal management of chemotherapy-related adverse events which are the nausea, vomiting, diarrhea, neutropenia, peripheral polyneuropathy. Recent literatures are reviewed and pathogenetic mechanism and management...
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Effectiveness of three different luteinizing hormone-releasing hormone agonists in the chemical castration of patients with prostate cancer: Goserelin versus triptorelin versus leuprolide

Shim M, Bang WJ, Oh CY, Lee YS, Cho JS

PURPOSE: To investigate the changes in testosterone levels and rates of chemical castration following androgen-deprivation therapy (ADT) with goserelin, triptorelin, and leuprolide. MATERIALS AND METHODS: We retrospectively reviewed the medical records...
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Factors Influencing Compliance with Safety Guidelines of Anticancer Drugs Among Nurses in General Hospitals

Jung J, Park JY

PURPOSE: The purpose of this study was to investigate the level of compliance with the safety guidelines of anticancer drugs and identify the factors influencing compliance among general characteristics, knowledge...
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The Treatments for Intermediate Risk Prostate Cancer

Shim M, Kwon T, Kim SC, Kim WS, Choo MS, Yeo JK

The population of intermediate-risk prostate cancer patients is a large heterogeneous group with diverse prognoses and challenges the struggle to develop more meticulous and standardized treatment recommendations. Furthermore, there are...
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Asian Society of Gynecologic Oncology International Workshop 2018

Kong TW, Ryu HS, Kim SC, Enomoto T, Li J, Kim KH, Shim SH, Wang PH, Therasakvichya S, Kobayashi , Lee M, Shi T, Lee SW, Mikami M, Nagase S, Lim MC, Wang J, Wilailak S, Kim SW, Hong SH, Tan DS, Mandai M, Chang SJ, Huang RY, Ushijima K, Lee JY, Chen X, Ochiai K, Lee TS, Yang B, Kalam F, Lv Q, Ahmad MF, Yaznil MR, Modi KB, Manopunya , Jeong DH, Lertkhachonsuk Aa, Chung HH, Watari H, Jeon S

The Asian Society of Gynecologic Oncology International Workshop 2018 on gynecologic oncology was held in the Ajou University Hospital, Suwon, Korea on the 24th to 25th August 2018. The workshop...
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Short-term Outcomes After Upfront Chemotherapy Followed by Curative Surgery in Metastatic Colon Cancer: A Comparison With Upfront Surgery Patients

Han MH, Park YY, Pratap S, Han YD, Cho MS, Hur H, Min BS, Lee KY, Kim NK

PURPOSE: Upfront systemic chemotherapy with target agents has been recommended for patients with stage IV colon cancer. Some with partial response are considered for curative resection. There is high risk...
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Status and Strategies for Safety Management of Antineoplastic Drugs among Oncology Nurses

Park JY, Noh GO, Kwon IG

PURPOSE: The purpose of this study was to identify the work environment related to the handling and administration of antineoplastic drugs in the members of the Korean Oncology Nursing Society. METHODS:...
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Histopathologic Study of Morbilliform Drug Eruption: Differences between Chemotherapeutic Agents and Antibiotics

Cho SY, Kwon JE, Han JH, Kim YC

  • KMID: 2436737
  • Korean J Dermatol.
  • 2018 Jul;56(6):368-375.
BACKGROUND: Cutaneous drug eruption is very common, and its clinical manifestations are variable. Diagnosis of drug eruption is usually based on clinical findings and medication history. To date, few studies...
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Perception and Practice to Safely Manage Antineoplastic Agents among Parents of Children with Cancer

Kim YS, Park JY

PURPOSE: The purpose of this study was to investigate perception and practice for safety management of antineoplastic agents among parents of children with cancer. METHODS: The study used questionnaires of 131...
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