J Rhinol.
2006 May;13(1):45-48.
A Case of Intranasal Pleomorphic Adenoma Arising from the Nasal Septum and Clivus
- Affiliations
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- 1Department of Otolaryngology-HNS, Collage of Medicine, The Catholic University of Korea, Seoul, Korea. yp@catholic.ac.kr
- 2Department of Clinical Pathology, Collage of Medicine, The Catholic University of Korea, Seoul, Korea.
Abstract
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Pleomorphic adenomas arise most commonly in the major salivary glands. It has rarely been described arising in the nasal cavity. A 65-year-old woman presented with a 9-month-history of left sided nasal obstruction. Endoscopic examination and computed tomographic scan revealed a lobulated tumor mass arising from the left bony nasal septum and clivus. It was removed endoscopically with endonasal approach. Histologic examination showed a lobular and duct-like structures consisting of a loose myxoid stoma consistent with characteristics of a pleomorphic adenoma. There was positive immunohistochemical expression of cytokeratin and S-100 protein which confirmed earlier histopathological diagnosis. We report a very rare case of pleomorphic adenoma originating from the nasal septum and clivus with a review of literature.