J Korean Ophthalmol Soc.  2005 Jun;46(6):1073-1078.

Multiple Myeloma Presented With Unilateral Ptosis: A Case Report

• Lee MJ
• Choung HK
• Khwarg SI
• Yang HJ

Abstract

PURPOSE
As orbital involvement in multiple myeloma is rare, the correct diagnosis is usually difficult. We report a case of multiple myeloma which involved the orbit, and which presented with unilateral ptosis. METHODS: A 35-year-old man was referred for the evaluation of ptosis of the left eyelid for 1 month. The levator function was normal, and there was no proptosis. Orbital computerized tomography (CT) revealed an orbital mass lesion involving the superior orbital ridge with intracranial extension. RESULTS: Excisional biopsy was performed through craniotomy and superior orbitotomy. Histopathologic examination and immunostaining result suggested a diagnosis of a plasmacytoma. The diagnosis of multiple myeloma was confirmed through bone marrow aspiration and biopsy showing diffuse infiltration of plasma cells. CONCLUSIONS: We experienced a case of multiple myeloma, which is rare in the orbit presenting unilateral ptosis. In addition, the possibility of orbital mass should be considered as an unusual cause of unilateral, acquired, progressive ptosis.

Keyword

Multiple myeloma; Orbital mass; Plasmacytoma; Ptosis

MeSH Terms

Adult
Biopsy
Bone Marrow
Craniotomy
Diagnosis
Exophthalmos
Eyelids
Humans
Multiple Myeloma*
Orbit
Plasma Cells
Plasmacytoma