J Korean Ophthalmol Soc.  2004 Dec;45(12):2036-2040.

Assessment of Retinal Ganglion Cell using Retinal Nerve Fiber Layer Photography in Age-related Macular Degeneration

Affiliations
  • 1Department of Ophthalmology, Seoul National University College of Medicine, Seoul, Korea. hgonyu@snu.ac.kr
  • 2Artificial Eye Laboratory, Seoul National University Hospital Clinical Research Institute, Seoul, Korea.

Abstract

PURPOSE
To determine the loss of ganglion cell layer (GCL) neurons in patients with age-related macular degeneration (AMD) with choroidal neovascularization (CNV). METHODS: Retinal nerve fiber layer (RNFL) photography was taken in patients with AMD with CNV to assess the presence of RNFL defects in the papillomacular bundle area. Patients with other ocular disorders or a history of previous intraocular surgery or laser treatment were excluded from this study. RESULTS: Eighty-five eyes in 65 patients were included, of which only one (1.2%) showed papillomacular bundle defects in association with CNV. CONCLUSIONS: From this study, the majority of the patients with AMD with CNV had no papillomacular bundle defect, which demonstrates that considerable amount of GCL is maintained in AMD.

Keyword

Age-related macular degeneration; Age-related maculopathy; Choroidal neovascularization; Papillomacular bundle defect; RNFL defect

MeSH Terms

Choroidal Neovascularization
Ganglion Cysts
Humans
Macular Degeneration*
Nerve Fibers*
Neurons
Photography*
Retinal Ganglion Cells*
Retinaldehyde*
Retinaldehyde
Full Text Links
  • JKOS
Actions
Cited
CITED
export Copy
Close
Share
  • Twitter
  • Facebook
Similar articles
Copyright © 2024 by Korean Association of Medical Journal Editors. All rights reserved.     E-mail: koreamed@kamje.or.kr