Korean J Ophthalmol.  2005 Mar;19(1):62-67. 10.3341/kjo.2005.19.1.62.

Thicknesses of Macular Retinal Layer and Peripapillary Retinal Nerve Fiber Layer in Patients with Hyperopic Anisometropic Amblyopia

• Yoon SW
• Park WH
• Baek SH
• Kong SM

• KMID: 1099087
• DOI: http://doi.org/10.3341/kjo.2005.19.1.62

Abstract

This prospective study was performed to measure the macular and the peripapillary retinal nerve fiber layer (RNFL) thicknesses using optical coherence tomography (OCT) in patients with anisometropic amblyopia. Thirty-one patients with hyperopic anisometropic amblyopia were included. The macular retinal thickness and the peripapillary RNFL thickness were measured using OCT. The mean refractive error was +3.71 diopters (D) and +1.00 D, the mean macular retinal thickness was 252.5 micrometer and 249.7 micrometer, and the mean RNFL thickness was 115.2 micrometer and 109.6 micrometer, in the amblyopic eye and the normal eye, respectively. OCT assessment of RNFL thickness revealed a significantly thicker RNFL in hyperopic anisometropic amblyopia (P=0.019), but no statistically significant difference was found in macular retinal thickness (P> 0.05). In conclusion, the amblyopic process may involve the peripapillary RNFL, but not the macula. However, further evaluation is needed.

Keyword

Hyperopic anisometropic amblyopia; Macular and retinal nerve fiber thickness; Optical coherence tomography

MeSH Terms

Amblyopia/complications/*pathology
Anisometropia/complications/*pathology
Child
Child, Preschool
Female
Humans
Macula Lutea/*pathology
Male
Nerve Fibers/*pathology
Optic Disk/*pathology
Prospective Studies
Retinal Ganglion Cells/*pathology
Tomography, Optical Coherence/methods

Figure

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  Fig. 1 Macular optical coherence tomography in a patient with hyperopic anisometropic amblyopia.

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  Fig. 2 Optical coherence tomography of retinal nerve fiber layer (RNFL) in a patient with hyperopic anisometropic amblyopia.

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  Fig. 3 Optical coherence tomography of retinal nerve fiber layer (RNFL) in the normal eye of a hyperopic anisometropic amblyopic patient.

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