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Enhanced Efficacy of Combined Therapy with Checkpoint Kinase 1 Inhibitor and Rucaparib via Regulation of Rad51 Expression in BRCA Wild-Type Epithelial Ovarian Cancer Cells

Cho Hy, Kim YB, Park Wh, No JH

Purpose This study aimed to evaluate anticancer effects of combination treatment with poly(ADP-ribose) polymerase (PARP) and checkpoint kinase 1 (Chk1) inhibitors in BRCA wild-type ovarian cancer. PARP inhibitors can function...
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High Serum-Induced AhRL Is Associated with Prevalent Metabolic Syndrome and Future Impairment of Glucose Tolerance in the Elderly

Pak YK, Choi HS, Park WH, Im S, Lind PM, Lind L, Lee HK

Background: High circulating levels of dioxins and dioxin-like chemicals, acting via the aryl hydrocarbon receptor (AhR), have previously been linked to diabetes. We now investigated whether the serum AhR ligands...
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Development and Utilization of a Rapid and Accurate Epidemic Investigation Support System for COVID-19

Park YJ, Cho SY, Lee J, Lee I, Park WH, Jeong S, Kim S, Lee S, Kim J, Park O

Objectives In this pandemic situation caused by a novel coronavirus disease in 2019 (COVID-19), an electronic support system that can rapidly and accurately perform epidemic investigations, is needed. It would systematically...
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Is Scapular Stabilization Exercise Effective for Managing Nonspecific Chronic Neck Pain?: A Systematic Review

Seo YG, Park WH, Lee CS, Kang KC, Min KB, Lee SM, Yoo JC

Scapular stabilization is thought to have an important role in improving pain and dysfunction around the neck and shoulders, but evidence of this is lacking. We aim to systematically review...
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Effect of Dialysis on Aryl Hydrocarbon Receptor Transactivating Activity in Patients with Chronic Kidney Disease

Kim JT, Kim SH, Min HK, Jeon SJ, Sung SA, Park WH, Lee HK, Choi HS, Pak YK, Lee SY

PURPOSE: Elevated aryl hydrocarbon receptor (AhR) transactivating (AHRT) activity and uremia in chronic kidney disease (CKD) may interact with each other, further complicating the disease course. In this study, we...
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Classification of nocturia by analyzing frequency volume chart and relations with international prostate symptom score in male patients with lower urinary tract symptoms in Korea

Choi YS, Kim JC, Kim YH, Choi JB, Park WH, Lee DH

PURPOSE: To evaluate the categories of nocturia and relationships with the international prostate symptom score (IPSS) in Korean men with lower urinary tract symptoms (LUTS) accompanying nocturia. MATERIALS AND METHODS: Five...
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Lumbar Extensor Muscle Size and Isometric Muscle Strength in Women with Symptomatic Lumbar Degenerative Diseases

Seo YG, Park WH, Lee CS, Kang KC

STUDY DESIGN: A cross-sectional design. PURPOSE: To determine the characteristics of lumbar extensor muscle (LEM) size and isometric muscle strength and examine their correlations in women with lumbar degenerative diseases (LDDs). OVERVIEW...
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Growth Behavior of Endothelial Cells According to Electrospun poly(D,L-Lactic-Co-Glycolic Acid) Fiber Diameter as a Tissue Engineering Scaffold

Ko YG, Park JH, Lee JB, Oh HH, Park WH, Cho D, Kwon OH

Investigating the effect of electrospun fiber diameter on endothelial cell proliferation provides an important guidance for the design of a fabric scaffold. In this study, we prepared biodegradable poly(D,L-lactic-co-glycolic acid)...
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Two Cases of Intravascular Lymphoma Presenting with Pulmonary Involvement

Moon JY, Park WH, Kim JM, Choi YS, Song IC, Lee HJ, Jo DY, Kim S, Yang YJ, Kim SS, Kim JH, Yun HJ

No abstract available.
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Implant esthetic restoration with bone graft in the extended maxillary anterior area: A case report

Jeong JW, Park SY, Kim YY, Park WH, Lee YS

The maxillary anteriors play an important role in esthetics. Therefore after extraction, it is crucial to preserve the hard tissue and soft tissue in order to promote esthetics of restoration....
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The Effect of Individualized Exercise Parameters Applied to Two Patients Recovering from Implanted Left Ventricular Assist Devices in Korea

Seo YG, Sung JD, Park WH

Left ventricular assist devices (LVADs) are a treatment option for patients with severe chronic heart failure. These patients are referred to an inpatient cardiac rehabilitation after implantation to improve an...
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Knee Muscle Strength after Revision Anterior Cruciate Ligament (ACL) Reconstruction: Comparison Primary ACL Reconstruction

Kim DK, Park WH

The purpose of this study was to assess the knee strength and anterior laxity in between primary and revision anterior cruciate ligament (ACL) reconstruction. It was a cross-sectional study; 28...
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Compound K attenuates stromal cell-derived growth factor 1 (SDF-1)-induced migration of C6 glioma cells

Kim H, Roh HS, Kim JE, Park SD, Park WH, Moon JY

BACKGROUND/OBJECTIVES: Stromal cell-derived growth factor 1 (SDF-1), also known as chemokine ligand 12, and chemokine receptor type 4 are involved in cancer cell migration. Compound K (CK), a metabolite of...
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Inflammatory Pseudotumor of the Liver Mimicking an Infiltrative Malignancy

Chung JH, Park WH, Lee JW, Yang JY, Ahn SY, Lee SH, Kim HS, Han SM

Inflammatory pseudotumor (IPT) is a relatively rare and benign disease characterized by chronic inflammatory cell infiltration with fibrosis. It is difficult to diagnose IPT because of the absence of specific...
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Gender Differences in Knee Laxity and Function after Anterior Cruciate Ligament Reconstruction

Kim DK, Park WH

Anterior cruciate ligament (ACL) reconstruction is frequently performed to restore knee stability and function following ACL injury. Little is known about the outcome differences between man and women patients after...
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Cytoprotective effect of rhamnetin on miconazole-induced H9c2 cell damage

Lee KP, Kim JE, Park WH

BACKGROUND/OBJECTIVES: Reactive oxygen species (ROS) formation is closely related to miconazole-induced heart dysfunction. Although rhamnetin has antioxidant effects, it remained unknown whether it can protect against miconazole-induced cardiomyocyte apoptosis. Thus,...
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Does a Low-wall Coverage Stent Have a Flow Diverting Effect in Small Aneurysms?

Liu H, Choe J, Jung SC, Song Y, Yang KH, Park KJ, Goo HW, Park WH, Suh DC

BACKBROUND AND PURPOSE: The flow diverting effect of a low-wall coverage stent remains controversial. We evaluted patients who underwent stenting for small aneurysms with a low but potential risk of...
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Full mouth rehabilitation of fully edentulous patient using implant hybrid prosthesis

Park SY, Kim YY, Park WH, Lee YS

Loss of teeth may not only imply impaired oral function and loss of alveolar bone but is also often accompanied by reduced self-confidence. This results in a larger problem with...
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Accuracy of Four Resting Metabolic Rate Predictive Equations in Obese Women

Kim DK, Park WH

Calculating the estimated resting metabolic rate (RMR) in severely obese patients is useful, but there is controversy concerning the effectiveness of available predictive equations using body weight. This study compared...
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The Clinical Outcomes of Exercise Therapy for a Soccer Player with Stress Fracture of Superior Pubic Ramus

Seo YG, Park WH

Stress fractures are common injuries that begin with repetitive and excessive stress on the bone. It is very rare that stress fracture was occurred in pubis superior ramus in athletics,...
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