J Korean Ophthalmol Soc.
1988 Oct;29(5):801-804.
The Antibacterial Sensitivity of Domestic Topical Antibiotics: in vitro test
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- 1Department of Ophthalmology, College of Medicine, Seoul National Uuiversity, Seoul, Korea.
Abstract
- The antibacterial activity of 11 domestic topical antibiotic eye drops were examed by use of Reddish method, in vitro test. 5 clinical strains which were recovered as common pathogens of corneal ulcer, were inoculated into the diluted antibiotics added with 1% human serum, and 0.01 ml were plated for bacterial survival at 0.5, 1, 2, 4, 8, 16. and 24 hours. Our result showed that gentamicin eye drops effective in Gram negative strains and penicil-line and cefazoline eye drops were effective in Gram positive strains. These results indicated that gentamicin and cefzolin eye drops in combination would be covered the common ocular pathogenic bacteria.
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