Korean J Prev Med.  1985 Oct;18(1):51-58.

A Study on the Validity of "Hepa-S" Hepatitis B antibody Detecting Reagent after Vaccination of "Hepa-Vax"

• Moon IS

Abstract

To attempt to measure the effect of domestic product P.H.A. kit "Hepa-S" after completion of "Hepa-Vax" vaccination schedule, P.H.A. test and R.I.A. test on the 330 healthy adults were carried out. The results obtained were as follow; 1. The positive anti HBs rate after completion of "Hepa-Vax" vaccination were; in P.H.A. test with domestic product P.H.A. kit 81.2%, in P.H.A. test with foreign product P.H.A. kit 82.7%, and in R.I.A. test 95.8%. 2. Using the result of R.I.A. test as the standard, sensitivity of P.H.A. test with domestic product P.H.A. kit was 84.8% and specificity was 100.0%. 3. Using the result of R.I.A. test as standard, sensitivity of P.H.A. test with foreign P.H.A. kit was 86.4% and specificity was 100.0%. 4. The concordance rate of P.H.A. test with domestic product and foreign product kit was 98.5%. On the result of this study, there was no significant difference in the validity between the domestic product P.H.A. kit "Hepa-S" and the foreign P.H.A. kit "HebsgencellTM". So that it is recommendable to use domestic product P.H.A. kit instead of foreign product P.H.A. kit.

MeSH Terms

Adult
Appointments and Schedules
Hepatitis B*
Hepatitis*
Humans
Sensitivity and Specificity
Vaccination*