J Korean Soc Plast Reconstr Surg.
2009 Jul;36(4):500-502.
Cutaneous Lipomatous Neurofibroma on the Lower Leg: A Case Report
- Affiliations
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- 1Department of Plastic Surgery, College of Medicine, The Catholic University of Korea, Seoul, Korea. jsn7190@catholic.ac.kr
Abstract
- PURPOSE
Cutaneous lipomatous neurofibroma is a rare variant of neurofibroma. Histologically, it includes adipose tissue. As far as we aware, only 11 cases of this variant were reported which was predominantly on head, neck and trunk. Hence we present a case of left pretibial area with literature review.
METHODS
The patient was a 17-year-old female who showed a non-tender, protruding 4x4x2cm sized mass on the left pretibial area for several months. We totally excised the mass including skin and the subcutaneous fat layer.
RESULTS
Pathologic report showed cutaneous lipomatous neurofibroma which was well circumscribed and noncapsulated neoplasm present with focal fatty change. Adipose cells were entrapped in the whirls of spindle cells. There were no lipoblasts or atypical adipocytes.
CONCLUSION
A cutaneous lipomatous neurofibroma on the lower extremity is very rare. In our patient, there were no trauma-related histopathologic changes. Therefore, focal fatty change can be a consequence of metaplasia from multipotential neural cells after migration.