Korean J Dermatol.  2008 Aug;46(8):1117-1119.

A Case of Lipomatous Neurofibroma

Affiliations
  • 1Department of Dermatology, School of Medicine, Ewha Womans University, Seoul, Korea. uwon313@ewha.ac.kr
  • 2Department of Dermatology, Ilsan Paik Hospital, Inje University School of Medicine1, Goyang, Korea.

Abstract

Lipomatous neurofibroma is a recently described, very rare variant of neurofibroma. It shows a well-circumscribed nodule consisting of fascicles or whorls of spindle cells with an extensive lipomatous component. These fat cells are considered to be an integral part of this tumor, not a metaplastic or degenerative process. It may be due to the differentiation of local stem cells of neural crest. Herein we report a case of lipomatous neurofibroma, the rare pathological variant of neurofibroma with extensive mature fat cells.

Keyword

Lipomatous; Neural crest; Neurofibroma

MeSH Terms

Adipocytes
Neural Crest
Neurofibroma
Stem Cells
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