J Korean Soc Plast Reconstr Surg.  1999 May;26(3):466-469.

The Clinical studies of Midazolam under Local Anesthesia for Aesthetic Surgery

• Lee SJ
• Park JH
• Cheo J

Abstract

In recent years there has been an increase in the number of outpatient surgical procedures performed using local anesthesia with intravenous sedation. However, many patients are reluctant to undergo surgery because of their concerns about pain and pain-awareness during the operation. We performed a study to evaluate the effectiveness and safety of midazolam during outpatient surgical procedures. Between March 1997 and December 1998, 50 patients were anesthetized with bolus intravenous injection of 0.1mg/kg of midazolam, followed by local anesthesia. The blood pressure, pulse and oximeter values were monitored. There was no significant change of arterial oxygen saturation. Midazolam induced antegrade amnesia in most cases. All patients except three (94%) said they would willingly choose this anesthetic technique again. Major complications were not noted. We concluded that midazolam is a good sedative agent in providing favorable antegrade amnesia, as well as reduced anxiety and fear of pain during surgical procedures. This suggests that midazolam may be used routinely in outpatient surgical procedures. Monitoring of oxygen saturation, however is essential in preventing severe hypoxia during procedures.

MeSH Terms

Amnesia
Anesthesia, Local*
Anoxia
Anxiety
Blood Pressure
Humans
Injections, Intravenous
Methods
Midazolam*
Outpatients
Oxygen
Midazolam
Oxygen