Tuberc Respir Dis.  2010 Oct;69(4):284-287. 10.4046/trd.2010.69.4.284.

Prostatic Stromal Tumor of Uncertain Malignant Potential (STUMP) Presenting with Multiple Lung Metastasis

• Lee HY
• Kim JJ
• Ko ES
• Kim SW
• Lee SH
• Kang HH
• Park CK
• Min KO
• Lee BY
• Moon HS
• Kang JY

• KMID: 2114623
• DOI: http://doi.org/10.4046/trd.2010.69.4.284

Abstract

We report the case of a 68-year-old man with a stromal tumor of uncertain malignant potential (STUMP), which had metastasized to the lung. The patient complained of an enlarged mass in the anterior chest. Chest computed tomography (CT) showed a sternal abscess with multiple nodules in both lungs. A thoracoscopic lung biopsy of the nodules and incision/drainage of the sternal mass were performed simultaneously. CT of the pelvis revealed an enlarged prostate with irregular cystic lesions in the pelvis. Prostate biopsy was done and demonstrated hypercellular stroma with minimal cytological atypia, a distinct pattern of STUMP. The sternal abscess proved to be tuberculosis and the lung lesion was consistent with STUMP, which had spread from the prostate. However, to our knowledge, the tuberculous abscess might not be assoicated with STUMP in the lung. The patient refused surgical prostatectomy and was discharged with anti-tuberculosis medication. On one-year follow up, the patient had no evidence of disease progression.

Keyword

Prostatic Neoplasms; Stromal Cells; Neoplasm Metastasis; Lung

MeSH Terms

Abscess
Aged
Biopsy
Disease Progression
Follow-Up Studies
Humans
Lung
Neoplasm Metastasis
Pelvis
Prostate
Prostatectomy
Prostatic Neoplasms
Stromal Cells
Thorax
Tuberculosis

Figure

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  Figure 1 Chest computed tomography reveals multiple round nodules scattered in the both lung fields.

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  Figure 2 Abdominopelvic computed tomography demonstrates an enlarged prostate with irregular cystic lesions (arrow) and a 2×1 cm sized nodular enhancing mass (arrowhead) in the right seminal vesicle.

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  Figure 3 Prostate biopsy shows moderately hypercellular stroma with no cytologic atypia, mitosis or necrosis (A, H&E stain, ×100). The tissues of lung lesion show moderately hypercellular stroma with no cytologic atypia, mitosis or necrosis, which findings are similar with those in prostate (B, H&E stain, ×40, C, H&E stain, ×100).

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