J Korean Ophthalmol Soc.  1987 Dec;28(6):1309-1314.

5-Fluorouracil and Glaucoma Filtering Surgery: I. Delayed administration

• Kim DM

Abstract

As fibroblasts proliferation at the sclerectomy wound is known to be vigorous after the fifth or sixth postoperative day, this study was performed to know if a delay in the administration of 5-fluorouracil until this time can still interfere with fibroblasts proliferation. The delayed onset of administration was seem to be efficacious. If this is more confirmed at further study, a decreased dose of postoperative 5-fluorouracil may interfere less with corneal wound healing.

MeSH Terms

Fibroblasts
Filtering Surgery*
Fluorouracil*
Glaucoma*
Wound Healing
Wounds and Injuries
Fluorouracil