J Korean Radiol Soc.  1994 Sep;31(3):405-410.

Perinatal Hypoxic-lschemic Brain Injury: MR Findings

• Park DW
• Seo CH

Abstract

PURPOSE
To characterize the MR findings of hypoxic-ischemic brain injury and to assess the value of the MR imaging.
MATERIALS AND METHODS
SE T1 -, T2-weighted, and IR brain MR images of 44 infants and children with the past history of perinatal hypoxic insults were reviewed. Abnormal brain MR findings of 8 patients with birth history of prematurity and 36 patients with birth history of full-term/posterm including 7 with severe anoxic insult history, were compared in regard to the location and the character of the lesions
RESULTS
MRI demonstrated the followings;(1)abnormal signal intensity lesions of subcortical and/or deep cerebral white matter, cortex, and deep gray matter, (2)atrophy of the cerebral white matter, cortex and corpus callosum, with/without ventriculomegaly, and (3)delay in myelination. Periventricular and deep white matter lesions were demonstrated in the prematurity, the deep white matter lesions and/or subcortical white matter lesions in the term/post-term, and deep gray matter lesions in the 7 patients with severe anoxic insults history.
CONCLUSION
MR imaging was useful in the diagnosis of the hypoxic-ischemic brain injury, and the white and gray matter lesions were correlated with the time of the injury and the severity of hypoxic insult.

MeSH Terms

Brain Injuries*
Brain*
Child
Corpus Callosum
Diagnosis
Humans
Infant
Magnetic Resonance Imaging
Myelin Sheath
Reproductive History