J Korean Soc Coloproctol.  2010 Oct;26(5):354-358. 10.3393/jksc.2010.26.5.354.

Surgical Resection for Lung Metastases from Colorectal Cancer

• Kim HJ
• Kye BH
• Lee JI
• Lee SC
• Lee YS
• Lee IK
• Kang WK
• Cho HM
• Moon SW
• Oh ST

• KMID: 2101531
• DOI: http://doi.org/10.3393/jksc.2010.26.5.354

Abstract

PURPOSE
The lung is the second most common site of metastasis from colorectal cancer. Of all patients who undergo a curative resection for colorectal cancer, 10% to 15% will develop lung metastasis. As a hepatic resection of colorectal liver metastases results in improved survival, many reports have suggested that a pulmonary resection of a colorectal lung metastasis would also improve survival. The aim of this study was to analyze the postoperative outcomes of and the prognostic factors for a surgical resection of a lung metastasis.
METHODS
Between August 1997 and March 2006, 27 patients underwent surgical resections for colorectal lung metastases at Seoul St. Mary's hospital. A retrospective review of patients' characteristics and various tumor factors was performed.
RESULTS
The mean interval between colorectal resection and lung metastasis was 24.0 +/- 15.1 months. The overall 3- and 5-year survival rates were 76.5% and 22.2%, respectively. The mean follow-up after pulmonary resection was 39.5 +/- 21.6 months (range, 3.3 to 115 months). Except for the existence of hilar-lymph-node metastasis (P < 0.001), no risk factors that we studied were statistically significant. Two patients had hilar-lymph-node metastasis. They survived for only for 3.3- and 11.6-months, respectively.
CONCLUSION
In our study, we found that a pulmonary resection for metastases from colorectal cancer may improve survival in selected patients.

Keyword

Colorectal neoplasms; Neoplasm metastasis; Lung

MeSH Terms

Colorectal Neoplasms
Follow-Up Studies
Humans
Liver
Lung
Neoplasm Metastasis
ortho-Aminobenzoates
Retrospective Studies
Risk Factors
Survival Rate
ortho-Aminobenzoates