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Meta-analysis of transanal versus laparoscopic total mesorectal excision for rectal cancer: a ‘New Health Technology’ assessment in South Korea

Kwon SH, Joo YI, Kim SH, Lee DH, Baek JH, Chung SS, Shin JY, Eun CS, Kim NK

Purpose: Under the South Korea’s unique health insurance structure, any new surgical technology must be evaluated first by the government in order to consider whether that particular technology can be...
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Adjuvant oxaliplatin-based chemotherapy effect after treatment of colorectal hepatic metastasis

Kang MY, Paik JH, Ryu CG, Hwang DY

Purpose: We aimed to investigate whether adjuvant oxaliplatin-based chemotherapy after treatment for hepatic metastasis affects recurrence or survival and to determine the risk factors for recurrence or survival. Methods: Forty-six patients...
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Risk of colorectal cancer in patients with positive results of fecal immunochemical test performed within 5 years since the last colonoscopy

Jung YS, Lee J, Moon CM

Background/Aims: Annual fecal immunochemical tests (FITs) are often repeated within the recommended colonoscopy surveillance intervals. However, it remains unclear whether interval FITs are useful. To answer this question, we assessed...
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Second-look endoscopy findings after endoscopic submucosal dissection for colorectal epithelial neoplasms

Park Sk, Goong HJ, Ko BM, Kim H, Seok HS, Lee MS

Background/Aims: Although second-look endoscopy (SLE) is frequently performed after gastric endoscopic submucosal dissection (ESD) to prevent bleeding, no studies have reported SLE findings after colorectal ESD. This study aimed to...
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Has the COVID-19 Pandemic Caused Upshifting in Colorectal Cancer Stage?

Lim JH, Lee WY, Yun SH, Kim HC, Cho YB, Huh JW, Park YA, Shin JK

Purpose: Coronavirus disease 2019 (COVID-19) has affected many parts of daily life and healthcare, including cancer screening and diagnosis. The purpose of this study was to determine whether there was...
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Clinical Outcomes of Neoadjuvant Chemotherapy in Colorectal Cancer Patients With Synchronous Resectable Liver Metastasis: A Propensity Score Matching Analysis

Park SH, Shin JK, Lee WY, Yun SH, Cho YB, Huh JW, Park YA, Heo JS, Choi GS, Kim ST, Park YS, Kim HC

Purpose: The survival benefit of neoadjuvant chemotherapy (NAC) prior to surgical resection in colorectal cancer with liver metastases (CRCLM) patients remains controversial. The aim of this study was to compare...
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Prognostic Factors Affecting Disease-Free Survival and Overall Survival in T4 Colon Cancer

Eom T, Lee Y, Kim J, Park I, Gwak G, Cho H, Yang K, Kim K, Bae BN

Purpose: It is known that as the T stage of a carcinoma progresses, the prognosis becomes poorer. However, there are few studies about factors that affect the prognosis of T4...
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Comparison of oncologic outcomes between patients with Lynch syndrome and sporadic microsatellite instability-high colorectal cancer

Son IT, Kim DW, Kim MH, Shin YK, Ku JL, Oh HK, Kang SB, Jeong SYJ, Park KJ

Purpose: Long-term oncologic differences in outcome between groups of patients with Lynch syndrome (LS) colorectal cancer (CRC) and sporadic CRC with microsatellite instability-high (MSI-H) are the focus of investigation in...
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White Opaque Substance, a New Optical Marker on Magnifying Endoscopy: Usefulness in Diagnosing Colorectal Epithelial Neoplasms

Yamasaki K, Hisabe T, Yao K, Ishihara H, Imamura K, Yasaka T, Tanabe H, Iwashita A, Ueki T

Background/Aims: A white substance that is opaque to endoscopic light is sometimes observed in the epithelium during narrowband imaging with magnifying endoscopy of gastric or colorectal epithelial neoplasms. This prospective...
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Risk of Death in Colorectal Cancer Patients with Multi-morbidities of Metabolic Syndrome: A Retrospective Multicohort Analysis

Feng Q, Xu L, Li L, Qiu J, Huang Z, Jiang Y, Wen T, Lu S, Meng F, Shu X

Purpose The prevalence of multi-morbidities with colorectal cancer (CRC) is known to be increasing. Particularly prognosis of CRC patients co-diagnosed with metabolic syndrome (MetSyn) was largely unknown. We aimed to...
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Optimal Maintenance Strategy for First-Line Oxaliplatin-Containing Therapy with or without Bevacizumab in Patients with Metastatic Colorectal Cancer: A Meta-Analysis

Moriwaki T, Gosho M, Sugaya A, Yamada T, Yamamoto Y, Hyodo I

Purpose Maintenance therapy after oxaliplatin withdrawal is useful in patients with metastatic colorectal cancer (mCRC). This study aimed to investigate the timing of discontinuation or reintroduction of oxaliplatin and the...
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Factors Associated with Clinical Outcomes of Palliative Stenting for Malignant Colonic Obstruction

Kwon SJ, Yoon J, Oh EH, Kim J, Ham NS, Hwang SW, Park SH, Ye BD, Byeon JS, Myung SJ, Yang SK, Yang DH

Background/Aims: Self-expandable metal stents (SEMSs) can be applied to relieve colorectal obstruction secondary to incurable primary colorectal cancer or extracolonic malignancy. We aimed to identify factors associated with clinical success...
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Application of deep learning to predict advanced neoplasia using big clinical data in colorectal cancer screening of asymptomatic adults

Yang HJ, Cho CW, Jang J, Kim SS, Ahn KS, Park SK, Park DI

Background/Aims: We aimed to develop a deep learning model for the prediction of the risk of advanced colorectal neoplasia (ACRN) in asymptomatic adults, based on which colorectal cancer screening could...
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Synchronous Quadruple Colon Cancer With Two Lesions Previously Obscured by Ischemic Colitis, Plus Bladder Cancer and Thymoma: A Case Report

Park BS, Cho SH, Kim SJ, Kim TU, Kim DI, Son GM, Kim HS

Synchronous quadruple colorectal cancer (CRC) is extremely rare without genetic alterations. We present a case of synchronous quadruple CRC with 2 lesions previously obscured by ischemic colitis. A 73-year-old woman...
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Multifunctional Indocyanine Green Applications for Fluorescence-Guided Laparoscopic Colorectal Surgery

Son GM, Ahn Hm, Lee IY, Ha GW

Indocyanine green (ICG) could be applied for multiple functions such as fluorescent tumor localization, fluorescence lymph node mapping (FLNM), and intraoperative angiography in colorectal cancer surgery. With the near-infrared (NIR)...
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Strategies for colorectal cancer screening and post-polypectomy surveillance for young adults under age 50

Jung YS

The incidence of colorectal cancer in young adults aged < 50 years is increasing. In line with these recent trends, it is necessary to pay attention to young-onset colorectal adenoma,...
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Diagnostic Performance of Deep Learning-Based Lesion Detection Algorithm in CT for Detecting Hepatic Metastasis from Colorectal Cancer

Kim K, Kim S, Han K, Bae H, Shin J, Lim JS

Objective: To compare the performance of the deep learning-based lesion detection algorithm (DLLD) in detecting liver metastasis with that of radiologists. Materials and Methods: This clinical retrospective study used 4386-slice computed...
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Feasibility and Outcomes of Multivisceral Resection in Locally Advanced Colorectal Cancer: Experience of a Tertiary Cancer Center in North-East India

Purkayastha J, Singh PR, Talukdar A, Das G, Yadav J, Bannoth S

Purpose: Locally advanced colorectal cancer may require an en bloc resection of surrounding organs or structures to achieve complete tumor removal. This decision must weigh the risk of complications of...
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Impact of nonalcoholic fatty liver disease on the risk of metachronous colorectal neoplasia after polypectomy

Kim NH, Jung YS, Park JH, Park DI, Sohn CI

Background/Aims: Metabolic syndrome has been reported to be a risk factor for metachronous colorectal neoplasia (CRN). However, the impact of nonalcoholic fatty liver disease (NAFLD), a hepatic manifestation of metabolic...
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Clinicopathological Characteristics and Surgical Outcomes of Crohn Disease-Associated Colorectal Malignancy

Lee YN, Lee JL, Yu CS, Kim JB, Lim SB, Park IJ, Yoon YS, Kim CW, Yang SK, Ye BD, Park SH, Kim JC

Purpose: Carcinoma arising from Crohn disease (CD) is rare, and there is no clear guidance on how to properly screen for at-risk patients and choose appropriate care. This study aimed...
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