J Korean Soc Magn Reson Med.  2012 Dec;16(3):271-275. 10.13104/jksmrm.2012.16.3.271.

MR Findings of Hamartoma of the Breast: A Report of Two Cases

• Nam SY
• Han BK
• Lee S
• Lee K

• KMID: 2099865
• DOI: http://doi.org/10.13104/jksmrm.2012.16.3.271

Abstract

Breast hamartoma is a relatively rare pathology, composed of various amount of mammary glandular, fatty and fibrous tissue. Here, we report MR findings of two cases of hamartomas; one of them was incidentally found in her left breast during preoperative MRI in a woman with right breast cancer, and the other was presented as a large palpable mass. Both of them were confirmed by surgical excision. Breast hamartoma shows a well-defined mass with mixed signal intensity on T2-weighted image MRI and a little or focal enhancement on contrast-enhanced MRI.

Keyword

Breast neoplasms; Hamartoma; Magnetic resonance imaging (MRI)

MeSH Terms

Breast
Breast Neoplasms
Female
Hamartoma
Humans

Figure

• 

  Fig. 1 A 44-year-old woman with hamartoma of the left breast. a. Axial T1-weighted spin echo MRI (TR/TE, 400/7) shows a 2 cm, oval shaped, circumscribed mass with central high signal intensity and peripheral iso signal intensity in left upper inner quadrant (arrow). b. Axial fat - suppressed fast spin echo T2-weighted MRI (TR/TE, 5000/70) shows a mass with central iso signal intensity, which was regarded as fat component and peripheral high signal intensity (arrow). c. Sagittal dynamic contrast-enhanced fat-suppressed T1-weighted image MRI shows mild peripheral nodular enhancement of the mass (arrows). d. The time-intensity curve obtained from the site of nodular enhancement during dynamic contrast enhanced MRI shows the presence of a gradual enhancement pattern. e. Second-look ultrasonogrpahy shows an oval shaped, circumscribed, hyperechoic mass in the left upper inner quadrant (arrows). f. Mediolateral mammogram shows a 2 cm, oval shaped, well-defined mass with internal fat density (arrows).

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  Fig. 2 A 48-year-old woman with hamartoma of the right breast. a, b. Craniocaudal and mediolateral mammograms of her right breast show a 7cm sized, oval shaped, circumscribed, isodense mass at palpable site of the right breast (arrows). c. Ultrasonography shows an oval shaped, circumscribed, heterogeneous and isoechoic mass (arrows). d. Axial T1-weighted spin echo MRI (TR/TE, 660/8) shows an oval shape, circumscribed mass with iso signal intensity (arrows). e. Axial fat - suppressed fast spin echo T2-weighted MRI (TR/TE, 5,500/70) shows a mass with mixed signal intensity (arrows). F. Sagittal dynamic contrast-enhanced fat-suppressed T1-weighted image MRI shows no enhancement except a little peripheral enhancement (arrow). g. Photomicrograph shows several small clusters of adipocytes within a densely fibrotic stroma (adipocyte (black arrows), glandular tissue (white arrows), fibrous tissue (black arrowheads), haematoxylin and eosin stained; original magnification, ×100).

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