J Korean Soc Pediatr Nephrol.  2004 Oct;8(2):159-165.

The Comparative Study of Clinical Manifestations in Acute Poststreptococcal Glomerulonephritis with Gross Hematuria or Microscopic Hematuria

• Park SH
• Chung ES
• Sim CE
• Lee CG
• Kim KH

Abstract

PURPOSE: This study aimed to compare the clinical outcome of acute poststreptocaccal glomerulonephritis (APSGN) between patients who had presented with gross hematuria and those with microscopic hematuria.
METHODS
Thirty-nine patients with acute poststreptococcal glomerulonephritis, who were diagnosed from January 2000 to April 2003 were enrolled.
RESULTS
The mean age was 8.85 years and the male to female ratio was 1.1:1. Seventeen patients presented with gross hematuria at diagnosis(group A) and twenty-two patients had microscopic hematuria only(group B). There were no significant differences between the two groups in the incidence of edema, fever or history of respiratory infection and oliguria. But hypertension was more frequent in group B. Laboratory data showed decreased C3 and C4 level in group B. Spot urine protein/creatinine ratio and 24hr urine protein showed higher levels in group A.
CONCLUSION
Patients with gross hematuria at diagnosis had lower incidence of hypertension and a higher rate of nephrotic range of proteinuria than patients with microscopic hematuria. However, no difference in the duration of admission or complication rate was observed. All patients had clinical improvement during follow-up. We conclude that gross hematuria is not a significant prognostic factor for poststreptococcal glomerulonephritis.

Keyword

Glomerulonephritis; Hematuria; Streptococcal infections

MeSH Terms

Diagnosis
Edema
Female
Fever
Follow-Up Studies
Glomerulonephritis*
Hematuria*
Humans
Hypertension
Incidence
Male
Oliguria
Proteinuria
Streptococcal Infections