Child Kidney Dis.  2016 Apr;20(1):6-10. 10.3339/jkspn.2016.20.1.6.

Clinical Manifestation Patterns and Trends in Poststreptococcal Glomerulonephritis

• Kim KH

• KMID: 2163317
• DOI: http://doi.org/10.3339/jkspn.2016.20.1.6

Abstract

Poststreptococcal glomerulonephritis (PSGN) is one of the most recognized diseases in pediatric nephrology. Typical clinical features include rapid onset of gross hematuria, edema, and hypertension, and cases are typically preceded by an episode of group A β-hemolytic streptococcus pharyngitis or pyoderma. The most common presenting symptoms of PSGN are the classic triad of glomerulonephritis: gross hematuria, edema, and hypertension . However, patients with PSGN sometimes present with unusual or atypical clinical symptoms that often lead to delayed diagnosis or misdiagnosis of the disease and increased morbidity. Additionally, the epidemiology of postinfectious glomerulonephritis (PIGN), including PSGN, has changed over the past few decades. This paper reviews atypical clinical manifestations of PSGN and discusses the changing demographics of PIGN with a focus on PSGN.

Keyword

Poststreptococcal; Glomerulonephritis; Postinfectious

MeSH Terms

Delayed Diagnosis
Demography
Diagnostic Errors
Edema
Epidemiology
Glomerulonephritis*
Hematuria
Humans
Hypertension
Nephrology
Pharyngitis
Pyoderma
Streptococcus