J Korean Surg Soc.  2011 Jun;80(Suppl 1):S59-S62. 10.4174/jkss.2011.80.Suppl1.S59.

Laparoscopic splenectomy for sclerosing angiomatoid nodular transformation of the spleen

Affiliations
  • 1Department of Surgery, Dong-A University College of Medicine, Busan, Korea. sshamee@dau.ac.kr
  • 2Department of Pathology, Dong-A University College of Medicine, Busan, Korea.

Abstract

Primary splenic tumors are rare and mainly found incidentally on radiologic studies. Among them, sclerosing angiomatoid nodular transformation (SANT) of the spleen is a new entity defined as a benign pathologic lesion. Most SANTs have no clinical symptoms and are occasionally accompanied by other splenic diseases such as malignancies. So, the exact diagnosis of the nature of the splenic tumor is mandatory for further treatment. But, preoperative diagnosis is not easy since it is difficult to obtain the tissue from the spleen for pathological study. Recently, laparoscopic splenectomy has become the more standard procedure for the spleen for diagnosis and treatment. Here, we report a rare case of SANT diagnosed following laparoscopic splenectomy.

Keyword

Laparoscopic splenectomy; Sclerosing angiomatoid nodular transformation

MeSH Terms

Spleen
Splenectomy
Splenic Diseases

Figure

  • Fig. 1 Preoperative abdominal computed tomography demonstrates an expansible low density mass (white arrow).

  • Fig. 2 Laparoscopic view of a splenic tumor.

  • Fig. 3 The spleen shows a well-demarcated, unencapsulated, dark brown mass with central stellate fibrotic scar on cut section.

  • Fig. 4 Microscopic findings in sclerosing angiomatoid nodular transformation of spleen. (A) The tumor shows multinodular lesion surrounded by fibrosis. The nodules are irregular and composed of many small-sized vessels. The fibrotic area shows abundant collagen fibers and inflammatory cells hematoxylin-eosin (H&E, ×40). (B) The high power view of angiomatoid nodular lesion, it shows many vessels, extravasated red blood cells and inflammatory cells (H&E, ×100).


Reference

1. Moriyama S, Inayoshi A, Kurano R. Inflammatory pseudotumor of the spleen: report of a case. Surg Today. 2000. 30:942–946.
2. Caraway NP, Fanning CV. Use of fine-needle aspiration biopsy in the evaluation of splenic lesions in a cancer center. Diagn Cytopathol. 1997. 16:312–316.
3. Stephens BJ, Justice JL, Sloan DA, Yoder JA. Elective laparoscopic splenectomy for hematologic disorders. Am Surg. 1997. 63:700–703.
4. Walsh RM, Brody F, Brown N. Laparoscopic splenectomy for lymphoproliferative disease. Surg Endosc. 2004. 18:272–275.
5. Martel M, Cheuk W, Lombardi L, Lifschitz-Mercer B, Chan JK, Rosai J. Sclerosing angiomatoid nodular transformation (SANT): report of 25 cases of a distinctive benign splenic lesion. Am J Surg Pathol. 2004. 28:1268–1279.
6. Teng X, Yu X, Wang G, Xu L, Lai M. Sclerosing angiomatoid nodular transformation of the spleen. Anal Quant Cytol Histol. 2008. 30:125–132.
7. Delaitre B, Maignien B. Splenectomy by the laparoscopic approach: report of a case. Presse Med. 1991. 20:2263.
8. Rosen M, Brody F, Walsh RM, Tarnoff M, Malm J, Ponsky J. Outcome of laparoscopic splenectomy based on hematologic indication. Surg Endosc. 2002. 16:272–279.
9. Lee SG, Kim MC, Kim HH, Kwon HC, Jung GJ. Treatment result of laparoscopic versus open splenectomy in benign splenic diseases. J Korean Surg Soc. 2005. 68:230–234.
10. Bellows CF, Sweeney JF. Laparoscopic splenectomy: present status and future perspective. Expert Rev Med Devices. 2006. 3:95–104.
Full Text Links
  • JKSS
Actions
Cited
CITED
export Copy
Close
Share
  • Twitter
  • Facebook
Similar articles
Copyright © 2024 by Korean Association of Medical Journal Editors. All rights reserved.     E-mail: koreamed@kamje.or.kr