Korean J Anesthesiol.  2005 Aug;49(2):131-135. 10.4097/kjae.2005.49.2.131.

Comparision of Prevention Effect of Lidocaine Pretreatment on Pain and Withdrawal Assosiated with Injection of Rocuronium

• Jung SS
• Lee JN
• Yoon SH

• KMID: 2092018
• DOI: http://doi.org/10.4097/kjae.2005.49.2.131

Abstract

BACKGROUND: Rocuronium bromide is a new steroidal nondepolarizing neuromusular blocking drug characterized by a rapid onset and intermediate duration of action. I.V. rocuronium produces intense discomfort at the site of injection, so many trials have been conducted on prevention of pain induced by I.V. rocuronium. This study evaluate venous retension induced forearm was squeezed with a tourniquet, affect lidocaine efficacy.
METHODS
Test was performed alert patients and unconscious patients. One group received lidocaine (0.5 mg/kg) and the other forearm was squeezed with tourniquet keeping the lidocaine (0.5 mg/kg) within the vein. After 30, 60 seconds rocuronium (0.6 mg/kg) was injected. propofol (2 mg/kg) induce patients unconsiousness.
RESULTS
There was statistical difference in reduction pain and withdrawal among groups. Squeezing group showed less pain and withdrawal than no squeezing group.
CONCLUSION
Venous retension induced forearm was squeezed with a tourniquet, lidocaine reduce pain and withdrawal movement more effectively.

Keyword

lidocaine; pain; rocuronium

MeSH Terms

Forearm
Humans
Lidocaine*
Propofol
Tourniquets
Veins
Lidocaine
Propofol