Korean J Anesthesiol.  1998 Jun;34(6):1237-1240. 10.4097/kjae.1998.34.6.1237.

Comparison of Intravenous Administration and Surgical Site Infiltration of Ketorolac Combined with Preincisional Infiltration of Bupivacaine

Affiliations
  • 1Department of Anesthesiology, College of Medicine, Dankook University, Cheon An, Korea.
  • 2Department of Obstetric and Gynecology, College of Medicine, Dankook University, Cheon An, Korea.

Abstract

BACKGROUND: We postulated that ketorolac as a component of surgical site infiltration would result in better analgesia than intravenous ketorolac.
METHODS
Sixty patients who scheduled for elective total abdominal hysterectomy received ketorolac 60 mg (2 ml) either via surgical site infiltration directly (n=30) or parenteral route (n=30) with surgical site infiltration of 0.25% bupivacaine 18 ml 20 min before skin incision.
RESULTS
Postoperative analgesic requirement, 48 hour total infusion dose and first 12 hour infusion dose of PCA fentanyl, were significantly lower in surgical site group. There were no significant differences in VAS score and side effects between two groups.
CONCLUSION
Ketorolac improves analgesia when it is administered in the surgical site.

Keyword

Analgesia: postoperative; Analgesics: ketorolac; Anesthetic techniques: infiltration; intravenous

MeSH Terms

Administration, Intravenous*
Analgesia
Bupivacaine*
Fentanyl
Humans
Hysterectomy
Ketorolac*
Passive Cutaneous Anaphylaxis
Skin
Bupivacaine
Fentanyl
Ketorolac
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