Korean J Blood Transfus.
2010 Aug;21(2):171-174.
Anti-Ok(a) Antibody: The First Case Report in Korea
- Affiliations
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- 1Department of Laboratory Medicine, Asan Medical Center and University of Ulsan College of Medicine, Seoul, Korea. swkwon@amc.seoul.kr
- 2Department of Orthopedic Surgery, Asan Medical Center and University of Ulsan College of Medicine, Seoul, Korea.
Abstract
- Anti-Ok(a) was detected in a 56-year-old female patient who was admitted for surgical treatment of degenerative scoliosis. Because Oka is a high-incidence antigen, anti-Ok(a) antibody is extremely rare. No case of hemolytic transfusion reaction or hemolytic disease of the fetus and newborn caused by anti-Ok(a) antibody has been reported so far, however, it is likely that anti-Ok(a) is clinically significant based on several in vivo and in vitro studies. When a patient who is bearing anti-Ok(a) needs transfusion of RBCs, transfusion of autologous blood or Ok(a-) RBCs from family members is recommended.
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