Korean J Anesthesiol.
2012 Oct;63(4):353-356. 10.4097/kjae.2012.63.4.353.
A case of acute hemolytic transfusion reaction due to anti-Di(a) antibody: A case report
- Affiliations
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- 1Department of Anesthesiology and Pain Medicine, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul, Korea. anesmun@hanmail.net
- KMID: 1767175
- DOI: http://doi.org/10.4097/kjae.2012.63.4.353
Abstract
- Many medical institutions in Korea have recently been performing an antibody screening test as one of the essential elements of a pre-transfusion test. The Dia antigen is well known as one of the antigens with low incidence among Caucasians; however, it has been discovered with a relatively higher incidence among Mongoloid populations. The frequency of the Dia antigen among the Korean population is estimated to be 6.4-14.5%. But in Korea, a screening panel of cells from abroad without Dia positive cells has been commonly used when a patient has an unexpected antibody screening test. Here we report a case of acute hemolytic transfusion reaction due to Anti-Dia antibody. To prevent other transfusion reaction by anti-Dia antibody, addition of Dia positive cells as unexpected antibody screening test is recommended.
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