Korean J Dermatol.
2003 Sep;41(9):1177-1186.
A Clinicopathologic Study on Hair Follicle Tumors
- Affiliations
-
- 1Department Dermatology, Dankook University, College of Medicine, Seoul, Korea. kyccc@dku.edu
- 2Department Dermatology, Ajou University, College of Medicine, Seoul, Korea.
- 3Department Dermatology, Ulsan University, College of Medicine, Seoul, Korea.
- 4Department Dermatology, Kyung Hee University, College of Medicine, Seoul, Korea.
- 5S&U Clinic, Korea.
- 6Department Dermatology, Catholic University of Daegu Schoool of Medicine, Korea.
- 7Department Dermatology, Korea University, College of Medicine, Seoul, Korea.
- 8Department Dermatology, Yonsei University, College of Medicine, Seoul, Korea.
- 9Department Dermatology, Hanyang University, College of Medicine, Seoul, Korea.
- 10Department Dermatology, Ewha Womans University, College of Medicine, Seoul, Korea.
- 11Department Dermatology, WonKwang University, College of Medicine, Seoul, Korea.
- 12Department Dermatology, Kosin University, College of Medicine, Seoul, Korea.
- 13Department Dermatology, National Medical Center, College of Medicine, Seoul, Korea.
- 14Department Dermatology, Youngnam University, College of Medicine, Seoul, Korea.
- 15Department Dermatology, Chonnam National University, College of Medicine, Seoul, Korea.
- 16Department Dermatology, Gyeongsang National University, College of Medicine, Seoul, Korea.
- 17Department Dermatology, Chungbuk National University, College of Medicine, Seoul, Korea.
- 18Department Dermatology, Sungkyunkwan University, College of Medicine, Seoul, Korea.
- 19Department Dermatology, Chungnam National University, College of Medicine, Seoul, Korea.
- 20Department Dermatology, Hallym University, College of Medicine, Seoul, Korea.
- 21Department Dermatology, Chonbuk National University, College of Medicine, Seoul, Korea.
- 22Department Dermatology, Seoul National University, College of Medicine, Seoul, Korea.
- 23Department Dermatology, Catholic University, College of Medicine, Seoul, Korea.
- 24Department Dermatology, Inha University, College of Medicine, Seoul, Korea.
- 25Department of Pathology, Hanyang University, College of Medicine, Seoul, Korea.
Abstract
- BACKGROUND
Data on the clinicopathologic features of hair follicle tumors in Korea are limited. OBJECTIVE: The purpose was to investigate the clinical and histopathologic characteristics of hair follicle tumors in Korea. METHODS: Two hundred sixty four cases of hair follicle tumors seen from 1999 to 2001 in Korea were analyzed clinically and histopathologically. RESULTS AND CONCLUSION: The most common hair follicle tumor in Korea was pilomatricoma(81.0%), followed by trichoepithelioma(6.4%), dilated pore of Winer(3.8%), and proliferating trichilemmal tumor(2.2%). Hair follicle tumors usually occurred as a solitary skin-colored nodule. The most commonly involved site was the face, and the peak age of presentation was 10 to 19. Pilomatricoma usually occurred as a solitary skin-colored nodule. The most commonly involved site was the arm, and more than 50% of tumors occurred before the age of 20. Histopathologically, the tumor was often surrounded by fibrous capsule and was composed of basophilic and shadow cells. It was usually located in the dermis and extended into the subcutis. Retraction spaces between tumor nests and stroma were frequently observed. Trichoepithelioma usually occurred as multiple skin-colored papules on the face. Histopathologically, the tumor was usually located in the dermis with sometimes connected to the epidermis. It frequently showed peripheral palisading. Dilated pore of Winer usually occurred as a solitary brownish to pigmented papule on the face in middle-aged persons. Proliferating trichilemmal tumor occurred as a solitary or multiple tumors. Histopathologically, the tumor was usually surrounded by incomplete fibrous capsule. Tumor cells frequently showed clear cell formation, nuclear atypia, mitosis, peripheral palisading, trichilemmal keratinization, and individual keratinization.
