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Hair Follicle Nevus Located on the Neck: Comparison with Accessory Tragus, Cervical Chondrocutaneous Branchial Remnants and Trichofolliculoma

Lee JS, Yang JH, Park H, Yoon HS, Cho S

Hair follicle nevus (HFN) is a rare, benign, follicular hamartoma that most frequently presents as a congenital nodule on the face. We experienced a rare case of HFN on the...
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Expression Pattern and Role of Klotho in Human Hair Follicles

Jin XH, Pi LQ, Lee WS

BACKGROUND: Klotho protein plays a pivotal role in aging regulation. However, it is unclear whether klotho is expressed in human hair follicles and is correlated with hair growth. OBJECTIVE: The purpose...
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Metformin, an Activator of AMPK, Promotes the Growth of Hair Follicles via the AMPK/β-catenin Signaling Pathway

Moon HR, Park KY, Kang HJ, Lee WJ, Won CH, Chang SE, Lee MW, Choi JH, Park GH

  • KMID: 2449198
  • Korean J Dermatol.
  • 2019 May;57(4):175-181.
BACKGROUND: AMP-activated protein kinase (AMPK) is a serine/threonine protein kinase that plays a pivotal role in the balance of cellular energy metabolism. Recent studies have reported that AMPK has numerous...
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MiR-214 Regulates the Human Hair Follicle Stem Cell Proliferation and Differentiation by Targeting EZH2 and Wnt/β-Catenin Signaling Way In Vitro

Du KT, Deng JQ, He XG, Liu ZP, Peng C, Zhang MS

miR-214 plays a major role in the self-renewal of skin tissue. However, whether miR-214 regulates the proliferation and differentiation of human hair follicle stem cells (HFSCs) is unknown. Primary HFSCs...
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Expression of p63 and its association with cell proliferation at different stages of murine hair follicle cycle

Lee BW, Oh JW, Seo M, Hwang JS, Yoon B

In the present study, we investigated the expression patterns of p63, a member of the p53 gene family, in hair follicle cells at different stages of the hair cycle and...
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Various Wavelengths of Light-Emitting Diode Light Regulate the Proliferation of Human Dermal Papilla Cells and Hair Follicles via Wnt/β-Catenin and the Extracellular Signal-Regulated Kinase Pathways

Joo HJ, Jeong KH, Kim JE, Kang H

BACKGROUND: The human dermal papilla cells (hDPCs) play an important role in regulation of hair cycling and growth. OBJECTIVE: The aim of this study was to investigate the effect of different...
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Attenuation of Dickkopf 1-Induced Hair Growth Inhibition in Cultured Human Hair Follicles by Tianeptine

Jeong HS, Kwack MH, Kim MK, Kim JC, Sung YK

No abstract available.
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3-Deoxysappanchalcone Promotes Proliferation of Human Hair Follicle Dermal Papilla Cells and Hair Growth in C57BL/6 Mice by Modulating WNT/β-Catenin and STAT Signaling

Kim YE, Choi HC, Lee IC, Yuk DY, Lee H, Choi BY

3-Deoxysappanchalcone (3-DSC) has been reported to possess anti-allergic, antiviral, anti-inflammatory and antioxidant activities. In the present study, we investigated the effects of 3-DSC on the proliferation of human hair follicle...
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Poor Capability of 3D-Cultured Adipose-Derived Stem Cells to Induce Hair Follicles in Contrast to 3D-Cultured Dermal Papilla Cells

Seo CH, Kwack MH, Lee SH, Kim MK, Kim JC, Sung YK

No abstract available.
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Protective effect of phloroglucinol against gamma radiation-induced oxidative stress in hair follicles

Kim A, Bing SJ, Cho J, Herath K, Jeon YJ, Lee BG, Park JW, Jee Y

When exposed to gamma-rays, hair follicular cells immediately go through apoptosis, which hampers their rapid differentiation essential for the regeneration of hair. Phloroglucinol (PG) is a phenolic compound of Ecklonia...
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Herbal Extracts Induce Dermal Papilla Cell Proliferation of Human Hair Follicles

Rastegar H, Ashtiani H, Aghaei M, Barikbin B, Ehsani A

BACKGROUND: The number of people suffering from balding or hair thinning is increasing, despite the advances in various medical therapies. Therefore, it is highly important to develop new therapies to...
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Simplified V-Shape Incision Technique for Saving Hair Follicles

Yeo IS, Shin SJ, Jang YJ, Park MC

BACKGROUND: The scalp is the second most visible part of the anatomy next to the face. Thus, aesthetic considerations such as scars and alopecia are important when planning excision of...
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Expression of Sfrp2 Is Increased in Catagen of Hair Follicles and Inhibits Keratinocyte Proliferation

Kim BK, Yoon SK

BACKGROUND: Hair follicles undergo cycles of repeated growth and regression. The Wnt pathway plays an important role in the regeneration and differentiation of hair follicles. Sfrp2, a Wnt inhibitor, is...
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A Case of Hair Follicle Nevus with Dermal Melanocytosis

Lee D, Lee JH, Kim SY, Kim KM

  • KMID: 2246439
  • Korean J Dermatol.
  • 2014 Jan;52(1):74-75.
No abstract available.
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The Analysis of the Expression of TGF-beta in Human Hair Follicles in vivo

Won CH, Joo YH, Lee DH, An JS, Kim BJ, Kwon OS, Cho KH, Kim KH, Eun HC

  • KMID: 1931110
  • Korean J Dermatol.
  • 2007 Apr;45(4):321-326.
BACKGROUND: Although it is well known that transforming growth factor beta (TGF-beta) may induce catagen change of hair follicles and inhibit hair growth, it is still unclear which subtype of...
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Hair Cycle-associated Changes of the Immunological Markers in Human Hair Follicles

Won CH, Oh JK, Lee MK, Lee SR, Li K, Choi CW, Kim KH, Cho KH, Eun HC

  • KMID: 2302345
  • Korean J Dermatol.
  • 2006 Jan;44(1):1-7.
BACKGROUND: The immunological characteristics of human hair follicles with the hair growth cycle have not yet been fully elucidated. It is suggested that expressional changes of the immunological markers in...
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Effects of Calcitonin Gene-Related Peptide on the Hair Growth in Human Hair Follicle Organ Culture

Oh TH, Lee EY, Lee S, Lee WS

  • KMID: 2302672
  • Korean J Dermatol.
  • 2005 Mar;43(3):342-351.
BACKGROUND: It has recently been reported that the peripheral nervous system has an important role in the hair growth and hair cycle change, which is mediated by neuropeptides. Furthermore, the...
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Effects of Substance P on the Expression of Various Factors to control Hair Growth in Human Hair Follicle Culture

Oh TH, Lee EY, Lee WS

  • KMID: 1605839
  • Korean J Dermatol.
  • 2004 Dec;42(12):1543-1551.
BACKGROUND: Among constituents of the skin, hair follicle is an organ where nerve fibers with the most highest density are distributed. Recently, it has been reported that neuropeptides, which are...
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Hair Follicles of Anterior Parietal Region are More Vulnerable than Occipital Region in Classic Acute Telogen Effluvium

Hong SS, Ihm CW, Lee MS

Background: The well known clinical feature of the classic acute telogen effluvium is diffuse hair loss from all over the scalp and the diagnosis is confirmed by a trichogram showing...
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A Clinicopathologic Study on Hair Follicle Tumors

Kim YC, Kang WH, Koh JK, Kim NI, Kim BS, Kim SW, Kim SN, Kim SC, Ro YS, Myung KB, Park SD, Bang D, Suh KS, Son SJ, Shin DH, Won YH, Oh CW, Yoon TY, Lee MW, Lee ES, Lee JH, Lee CH, Ihm CW, Cho KH, Cho BK, Choi GS, Hahm JH, Park CK

  • KMID: 2086711
  • Korean J Dermatol.
  • 2003 Sep;41(9):1177-1186.
BACKGROUND: Data on the clinicopathologic features of hair follicle tumors in Korea are limited. OBJECTIVE: The purpose was to investigate the clinical and histopathologic characteristics of hair follicle tumors in...
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