Korean J Dermatol.
2000 Feb;38(2):231-235.
A Case of Cephalic Brain-like Heterotopia
- Affiliations
-
- 1Department of Dermatology, Collage of Medicine, Inje University
Seoul, Korea.
- 2Department of Pathology, Collage of Medicine, Inje University
Seoul, Korea.
Abstract
-
Cephalic brain-like heterotopias, so called nasal gliomas, are masses of mature glial
tissue resulted from an error in embryonic development and are frequently located on the
bridge of the nose. They often give rise to the clinical suspicion of dermoid cyst,
hemangioma, or lipoma. Histologically, they are composed of fibrillary neuroglial cells,
mainly large astrocytes, which are interlaced with a variable amount of fibrous and vascular
connective tissue. Mitoses are rare. The possible tumor stalk is usually fibrous without
glial elements. Due to the occasional presence of connection to the intracranial space it
deserves a careful preoperative evaluation including imaging studies. We report a case of
cephalic brain-like heterotopia. A sixteen day-old infant presented a mass which was
suspended to the forehead by a fibrous stalk. Th excised lesion showed characteristic
pathologic features of cephalic brain-like heterotopia.