Korean J Dermatol.  2000 Feb;38(2):231-235.

A Case of Cephalic Brain-like Heterotopia

Affiliations
  • 1Department of Dermatology, Collage of Medicine, Inje University Seoul, Korea.
  • 2Department of Pathology, Collage of Medicine, Inje University Seoul, Korea.

Abstract

Cephalic brain-like heterotopias, so called nasal gliomas, are masses of mature glial tissue resulted from an error in embryonic development and are frequently located on the bridge of the nose. They often give rise to the clinical suspicion of dermoid cyst, hemangioma, or lipoma. Histologically, they are composed of fibrillary neuroglial cells, mainly large astrocytes, which are interlaced with a variable amount of fibrous and vascular connective tissue. Mitoses are rare. The possible tumor stalk is usually fibrous without glial elements. Due to the occasional presence of connection to the intracranial space it deserves a careful preoperative evaluation including imaging studies. We report a case of cephalic brain-like heterotopia. A sixteen day-old infant presented a mass which was suspended to the forehead by a fibrous stalk. Th excised lesion showed characteristic pathologic features of cephalic brain-like heterotopia.

Keyword

Cephalic brain - like heterotopia

MeSH Terms

Astrocytes
Connective Tissue
Dermoid Cyst
Embryonic Development
Female
Forehead
Glioma
Hemangioma
Humans
Infant
Lipoma
Mitosis
Neuroglia
Nose
Pregnancy
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