Korean J Hematol.  1997 May;32(1):146-151.

A Case of AILD-like T Cell Lymphoma with Monoclonal Gammopathy

Affiliations
  • 1Department of Internal Medicine, Hanyang University College of Medicine, Seoul, Korea.
  • 2Department of Clinical Pathology, Hanyang University College of Medicine, Seoul, Korea.
  • 3Department of Pathology, Hanyang University College of Medicine, Seoul, Korea.

Abstract

We report a case of 74 year old man presented with generalized lymphadenopathy with hepatosplenomegaly. Lymph node biopsy revealed angioimmunoblastic lymphadenopathy with dysproteinemia (AILD) and most areas of lymph node were replaced with large atypical lymphocytes which were revealed to be T cells by immunohistochemistry. All together, the patient was diagnosed as AILD-like T cell lymphoma with bone marrow involvement. The patient presented monoclonal gammopathy (IgG lambda) without any evidence of plasma cell dyscrasia or secondary amyloidosis. After three cycles of combination chemotherapy including cyclophosphamide, prednisone, vincristine and doxorubicin, the patient achieved partial remission with decreased level of serum and urine monoclonal protein.

Keyword

AILD-like T cell lymphoma; Monoclonal gammopathy

MeSH Terms

Aged
Amyloidosis
Biopsy
Bone Marrow
Cyclophosphamide
Doxorubicin
Drug Therapy, Combination
Humans
Immunoblastic Lymphadenopathy
Immunohistochemistry
Lymph Nodes
Lymphatic Diseases
Lymphocytes
Lymphoma, T-Cell*
Paraproteinemias*
Prednisone
T-Lymphocytes
Vincristine
Cyclophosphamide
Doxorubicin
Prednisone
Vincristine
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