Korean J Med Mycol.  2008 Dec;13(4):176-180.

A Case of Trichophytic Granuloma of the Leg Caused by Trichophyton rubrum

Affiliations
  • 1Department of Dermatology, College of Medicine, Dongguk University, Gyeongju, Korea. smg@dongguk.ac.kr
  • 2Department of Laboratory Medicine, College of Medicine, Dongguk University, Gyeongju, Korea.
  • 3Department of Pathology, College of Medicine, Dongguk University, Gyeongju, Korea.

Abstract

Dermatophytes usually do not invade beyond the epidermis. However, mechanical breakage of the skin resulting from scratching or trauma and immunocompromised state, such as diabetes mellitus, lymphoma, and long term steroid use may allow penetration of the fungi into dermis. We report a case of trichophytic granuloma of the thigh caused by Trichophyton(T.) rubrum in a 21-year-old chinese male, who showed a pruritic, 17x10 cm sized, erythematous to brownish patch with multiple papules on the left thigh for 3 months. Fungal culture of the biopsy specimen grew out typical white cottony colonies of T. rubrum. Histopathologic examination of the skin lesions showed chronic granulomatous inflammation and fungal elements in the dermis. After one month of itraconazole therapy (200 mg/day), lesions were completely cleared.

Keyword

Trichophytic granuloma; Thigh; Trichophyton rubrum

MeSH Terms

Arthrodermataceae
Asian Continental Ancestry Group
Biopsy
Dermis
Diabetes Mellitus
Epidermis
Fungi
Granuloma
Humans
Inflammation
Itraconazole
Leg
Lymphoma
Male
Skin
Thigh
Trichophyton
Young Adult
Itraconazole
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